NEW EVALUATION METHOD FOR EFFICACY OF HYPOTENSIVE TREATMENT WITH ACE INHIBITORS

The work, using Enam as an example, provides a new original evaluation method for hypotensive action of drugs. The method is based upon primary analysis of daily blood pressure monitoring data with subsequent transformation into a graphic form of BP values likelihood distribution over a plane. The a...

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Bibliographic Details
Main Authors: V. V. Shkarin, O. S. Belykh, E. V. Gurvich, E. A. Olkhovskaya, L. G. Yefremova, A. V. Tsiganova, U. Y. Ruzhentsova, N. T. Shilina, N. V. Sidorova
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2003-06-01
Series:Российский кардиологический журнал
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Online Access:https://russjcardiol.elpub.ru/jour/article/view/1753
Description
Summary:The work, using Enam as an example, provides a new original evaluation method for hypotensive action of drugs. The method is based upon primary analysis of daily blood pressure monitoring data with subsequent transformation into a graphic form of BP values likelihood distribution over a plane. The authors called the image obtained in this manner hypertension areal. The authors distinguish a core and a peripheral part of hypertension areal, proposing an evaluation method for many characteristic parameters. Hypotensive action is evaluated by changes in areal square over time. Patients receiving Enam were divided into 3 groups depending on the extent of hypotensive effect, by means of a neural network. Hypotensive effect is characterized based on the proposed standpoints for each group.
ISSN:1560-4071
2618-7620