Decreased humoral immune response in the bronchi of rapid decliners with chronic obstructive pulmonary disease

Decreased humoral immune response in the bronchi of rapid decliners with chronic obstructive pulmonary disease

Abstract Background Identification of COPD patients with a rapid decline in FEV1 is of particular interest for prognostic and therapeutic reasons. Objective To determine the expression of markers of inflammation in COPD patients with rapid functional decline in comparison to slow or no decliners. Me...

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Bibliographic Details
Main Authors: Antonino Di Stefano, Francesca Dossena, Isabella Gnemmi, Silvestro Ennio D’Anna, Paola Brun, Bruno Balbi, Alessio Piraino, Antonio Spanevello, Francesco Nucera, Vitina Carriero, Francesca Bertolini, Mauro Maniscalco, Ian M. Adcock, Gaetano Caramori, Fabio L. M. Ricciardolo
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Respiratory Research
Subjects:
Airway inflammation
Sustainers
Functional FEV1 decline
pIgR
IgA
Plasma cells
Online Access:https://doi.org/10.1186/s12931-022-02125-3

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