Hypoxia in Cell Reprogramming and the Epigenetic Regulations
Cellular reprogramming is a fundamental topic in the research of stem cells and molecular biology. It is widely investigated and its understanding is crucial for learning about different aspects of development such as cell proliferation, determination of cell fate and stem cell renewal. Other factor...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2021-01-01
|
| Series: | Frontiers in Cell and Developmental Biology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fcell.2021.609984/full |
| _version_ | 1818734713298223104 |
|---|---|
| author | Nariaki Nakamura Xiaobing Shi Radbod Darabi Yong Li |
| author_facet | Nariaki Nakamura Xiaobing Shi Radbod Darabi Yong Li |
| author_sort | Nariaki Nakamura |
| collection | DOAJ |
| description | Cellular reprogramming is a fundamental topic in the research of stem cells and molecular biology. It is widely investigated and its understanding is crucial for learning about different aspects of development such as cell proliferation, determination of cell fate and stem cell renewal. Other factors involved during development include hypoxia and epigenetics, which play major roles in the development of tissues and organs. This review will discuss the involvement of hypoxia and epigenetics in the regulation of cellular reprogramming and how interplay between each factor can contribute to different cellular functions as well as tissue regeneration. |
| first_indexed | 2024-12-18T00:09:44Z |
| format | Article |
| id | doaj.art-99ea8ec2981e4718b931fede020a4494 |
| institution | Directory Open Access Journal |
| issn | 2296-634X |
| language | English |
| last_indexed | 2024-12-18T00:09:44Z |
| publishDate | 2021-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cell and Developmental Biology |
| spelling | doaj.art-99ea8ec2981e4718b931fede020a44942022-12-21T21:27:42ZengFrontiers Media S.A.Frontiers in Cell and Developmental Biology2296-634X2021-01-01910.3389/fcell.2021.609984609984Hypoxia in Cell Reprogramming and the Epigenetic RegulationsNariaki Nakamura0Xiaobing Shi1Radbod Darabi2Yong Li3Department of Orthopaedic Surgery, and Biomedical Engineering, Homer Stryker M.D. School of Medicine, Western Michigan University, Kalamazoo, MI, United StatesCenter for Epigenetics, Van Andel Research Institute, Grand Rapids, MI, United StatesThe Center for Stem Cell and Regenerative Medicine (CSCRM), Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases (IMM), Houston, TX, United StatesDepartment of Orthopaedic Surgery, and Biomedical Engineering, Homer Stryker M.D. School of Medicine, Western Michigan University, Kalamazoo, MI, United StatesCellular reprogramming is a fundamental topic in the research of stem cells and molecular biology. It is widely investigated and its understanding is crucial for learning about different aspects of development such as cell proliferation, determination of cell fate and stem cell renewal. Other factors involved during development include hypoxia and epigenetics, which play major roles in the development of tissues and organs. This review will discuss the involvement of hypoxia and epigenetics in the regulation of cellular reprogramming and how interplay between each factor can contribute to different cellular functions as well as tissue regeneration.https://www.frontiersin.org/articles/10.3389/fcell.2021.609984/fullhypoxiaepigeneticmusclecellular reprogrammingstem cells |
| spellingShingle | Nariaki Nakamura Xiaobing Shi Radbod Darabi Yong Li Hypoxia in Cell Reprogramming and the Epigenetic Regulations Frontiers in Cell and Developmental Biology hypoxia epigenetic muscle cellular reprogramming stem cells |
| title | Hypoxia in Cell Reprogramming and the Epigenetic Regulations |
| title_full | Hypoxia in Cell Reprogramming and the Epigenetic Regulations |
| title_fullStr | Hypoxia in Cell Reprogramming and the Epigenetic Regulations |
| title_full_unstemmed | Hypoxia in Cell Reprogramming and the Epigenetic Regulations |
| title_short | Hypoxia in Cell Reprogramming and the Epigenetic Regulations |
| title_sort | hypoxia in cell reprogramming and the epigenetic regulations |
| topic | hypoxia epigenetic muscle cellular reprogramming stem cells |
| url | https://www.frontiersin.org/articles/10.3389/fcell.2021.609984/full |
| work_keys_str_mv | AT nariakinakamura hypoxiaincellreprogrammingandtheepigeneticregulations AT xiaobingshi hypoxiaincellreprogrammingandtheepigeneticregulations AT radboddarabi hypoxiaincellreprogrammingandtheepigeneticregulations AT yongli hypoxiaincellreprogrammingandtheepigeneticregulations |