Mendelian randomization analysis reveals causal relationship between tonsillectomy and irritable bowel syndrome

Mendelian randomization analysis reveals causal relationship between tonsillectomy and irritable bowel syndrome

ObjectiveThis study used two sample Mendelian randomization (MR) method to evaluate the causal relationship between tonsillectomy and irritable bowel syndrome (IBS).MethodsWe selected tonsillectomy as the exposure factor and IBS as the outcome variable, using GWAS data from the IEU Open GWAS project...

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Bibliographic Details
Main Authors: Huaiquan Liu, Shuoshuo Shao, Bo Chen, Shili Yang, Xinyan Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Surgery
Subjects:
tonsillectomy
irritable bowel syndrome
Mendelian randomization
causal relationship
instrumental variables
Online Access:https://www.frontiersin.org/articles/10.3389/fsurg.2025.1436227/full

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