The Danish Heart Failure Registry: A Validation Study of Content
Christina Andersen,1 Inge Schjødt,1 Anne Nakano,2 Søren Paaske Johnsen,3 Kenneth Egstrup,4 Brian B Løgstrup1,5 1Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark; 2The Danish Clinical Registries (RKKP), Aarhus, Denmark; 3Danish Center for Clinical Health Services Research (DACS),...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2022-12-01
|
| Series: | Clinical Epidemiology |
| Subjects: | |
| Online Access: | https://www.dovepress.com/the-danish-heart-failure-registry-a-validation-study-of-content-peer-reviewed-fulltext-article-CLEP |
| _version_ | 1797974852471095296 |
|---|---|
| author | Andersen C Schjødt I Nakano A Johnsen SP Egstrup K Løgstrup BB |
| author_facet | Andersen C Schjødt I Nakano A Johnsen SP Egstrup K Løgstrup BB |
| author_sort | Andersen C |
| collection | DOAJ |
| description | Christina Andersen,1 Inge Schjødt,1 Anne Nakano,2 Søren Paaske Johnsen,3 Kenneth Egstrup,4 Brian B Løgstrup1,5 1Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark; 2The Danish Clinical Registries (RKKP), Aarhus, Denmark; 3Danish Center for Clinical Health Services Research (DACS), Department of Clinical Medicine, Aalborg University, Aalborg, Denmark; 4Department of Cardiology, Odense University Hospital, Svendborg, Denmark; 5Institute of Clinical Medicine, Aarhus University, Aarhus, DenmarkCorrespondence: Brian B Løgstrup, Department of Cardiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, Aarhus, 8200, Denmark, Email bbl@skejby.rm.dkBackground: The Danish Heart Failure Registry (DHFR) is a clinical quality database established to monitor and improve the quality of heart failure (HF) care in Denmark.Objective: We examined the validity of the content of the DHFR.Methods: In a random sample of patients registered in DHFR between the 1st of January 2016 to the 31st of December 2018, we determined the agreement between the information entered in the database and information in the medical records regarding 1) content; 2) sensitivity; 3) specificity; 4) positive predictive values (PPV) as well as negative predictive values (NPV) of all patient characteristics and performance measures obtained in the DHFR.Results: The study population included 453 patients. In general, the content of the DHFR was accurate. Patient characteristics showed high PPV between 93.0% and 99.5% for all variables. Sensitivity ranged from 81.0% to 95.2%, specificity from 79.8% to 99.5% and NPV ranged from 81.4% to 99.0%. The pharmacological performance measures showed high agreement regarding sensitivity (77.4% to 98.6%) and PPV (84.0% to 94.0%). Further, the specificity ranged from 66.7% to 98.0% and NPP ranged from 90.1% to 96.5%. For the non-pharmacological performance measures, patient education showed high sensitivity (98.0%, 95% CI 96.1– 99.1) and PPV (94.9% CI: 93.0– 96.3), whereas referral to exercise training had a lower sensitivity of 77.8% (CI: 71.6– 83.1) and a PPV of 74.5% (CI: 69.6– 78.6).Conclusion: Overall, the Danish Heart Failure Registry have a high degree of completeness and validity, making it a valuable tool for clinical epidemiological research in HF.Keywords: heart failure, database, epidemiology, registries, Danish Heart Failure Registry |
| first_indexed | 2024-04-11T04:26:15Z |
| format | Article |
| id | doaj.art-99ee055a70ae42f3a113be50ce05af17 |
| institution | Directory Open Access Journal |
| issn | 1179-1349 |
| language | English |
| last_indexed | 2024-04-11T04:26:15Z |
| publishDate | 2022-12-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Clinical Epidemiology |
| spelling | doaj.art-99ee055a70ae42f3a113be50ce05af172022-12-29T17:48:02ZengDove Medical PressClinical Epidemiology1179-13492022-12-01Volume 141585159480614The Danish Heart Failure Registry: A Validation Study of ContentAndersen CSchjødt INakano AJohnsen SPEgstrup KLøgstrup BBChristina Andersen,1 Inge Schjødt,1 Anne Nakano,2 Søren Paaske Johnsen,3 Kenneth Egstrup,4 Brian B Løgstrup1,5 1Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark; 2The Danish Clinical Registries (RKKP), Aarhus, Denmark; 3Danish Center for Clinical Health Services Research (DACS), Department of Clinical Medicine, Aalborg University, Aalborg, Denmark; 4Department of Cardiology, Odense University Hospital, Svendborg, Denmark; 5Institute of Clinical Medicine, Aarhus University, Aarhus, DenmarkCorrespondence: Brian B Løgstrup, Department of Cardiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, Aarhus, 8200, Denmark, Email bbl@skejby.rm.dkBackground: The Danish Heart Failure Registry (DHFR) is a clinical quality database established to monitor and improve the quality of heart failure (HF) care in Denmark.Objective: We examined the validity of the content of the DHFR.Methods: In a random sample of patients registered in DHFR between the 1st of January 2016 to the 31st of December 2018, we determined the agreement between the information entered in the database and information in the medical records regarding 1) content; 2) sensitivity; 3) specificity; 4) positive predictive values (PPV) as well as negative predictive values (NPV) of all patient characteristics and performance measures obtained in the DHFR.Results: The study population included 453 patients. In general, the content of the DHFR was accurate. Patient characteristics showed high PPV between 93.0% and 99.5% for all variables. Sensitivity ranged from 81.0% to 95.2%, specificity from 79.8% to 99.5% and NPV ranged from 81.4% to 99.0%. The pharmacological performance measures showed high agreement regarding sensitivity (77.4% to 98.6%) and PPV (84.0% to 94.0%). Further, the specificity ranged from 66.7% to 98.0% and NPP ranged from 90.1% to 96.5%. For the non-pharmacological performance measures, patient education showed high sensitivity (98.0%, 95% CI 96.1– 99.1) and PPV (94.9% CI: 93.0– 96.3), whereas referral to exercise training had a lower sensitivity of 77.8% (CI: 71.6– 83.1) and a PPV of 74.5% (CI: 69.6– 78.6).Conclusion: Overall, the Danish Heart Failure Registry have a high degree of completeness and validity, making it a valuable tool for clinical epidemiological research in HF.Keywords: heart failure, database, epidemiology, registries, Danish Heart Failure Registryhttps://www.dovepress.com/the-danish-heart-failure-registry-a-validation-study-of-content-peer-reviewed-fulltext-article-CLEPheart failuredatabaseepidemiologyregistriesdanish heart failure registry |
| spellingShingle | Andersen C Schjødt I Nakano A Johnsen SP Egstrup K Løgstrup BB The Danish Heart Failure Registry: A Validation Study of Content Clinical Epidemiology heart failure database epidemiology registries danish heart failure registry |
| title | The Danish Heart Failure Registry: A Validation Study of Content |
| title_full | The Danish Heart Failure Registry: A Validation Study of Content |
| title_fullStr | The Danish Heart Failure Registry: A Validation Study of Content |
| title_full_unstemmed | The Danish Heart Failure Registry: A Validation Study of Content |
| title_short | The Danish Heart Failure Registry: A Validation Study of Content |
| title_sort | danish heart failure registry a validation study of content |
| topic | heart failure database epidemiology registries danish heart failure registry |
| url | https://www.dovepress.com/the-danish-heart-failure-registry-a-validation-study-of-content-peer-reviewed-fulltext-article-CLEP |
| work_keys_str_mv | AT andersenc thedanishheartfailureregistryavalidationstudyofcontent AT schjødti thedanishheartfailureregistryavalidationstudyofcontent AT nakanoa thedanishheartfailureregistryavalidationstudyofcontent AT johnsensp thedanishheartfailureregistryavalidationstudyofcontent AT egstrupk thedanishheartfailureregistryavalidationstudyofcontent AT løgstrupbb thedanishheartfailureregistryavalidationstudyofcontent AT andersenc danishheartfailureregistryavalidationstudyofcontent AT schjødti danishheartfailureregistryavalidationstudyofcontent AT nakanoa danishheartfailureregistryavalidationstudyofcontent AT johnsensp danishheartfailureregistryavalidationstudyofcontent AT egstrupk danishheartfailureregistryavalidationstudyofcontent AT løgstrupbb danishheartfailureregistryavalidationstudyofcontent |