The role and place of adequate nutrition in optimizing management of diabetes mellitus type 2
Inadequate nutrition prevents patients with type 2 diabetes (T2DM) from achieving target values of glycemic and non-glycemic parameters. Aim: to evaluate metabolic effects of the balanced diet including specialized nutrition (SN). Material and methods: the randomized clinical trial included 60 patie...
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| Format: | Article |
| Language: | Russian |
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Remedium Group LLC
2016-12-01
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| Series: | Медицинский совет |
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| Online Access: | https://www.med-sovet.pro/jour/article/view/68 |
| _version_ | 1797842117680168960 |
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| author | А. S. Ametov L. L. Kamynina N. A. Chernikova M. A. Dzhusoeva |
| author_facet | А. S. Ametov L. L. Kamynina N. A. Chernikova M. A. Dzhusoeva |
| author_sort | А. S. Ametov |
| collection | DOAJ |
| description | Inadequate nutrition prevents patients with type 2 diabetes (T2DM) from achieving target values of glycemic and non-glycemic parameters. Aim: to evaluate metabolic effects of the balanced diet including specialized nutrition (SN). Material and methods: the randomized clinical trial included 60 patients with type 2 diabetes treated with a double combination metformin + glibenclamide, who were divided into 2 groups. Patients in the treatment group received SN Glucerna SR which replaced the main meal; the comparison group of patients were on a natural low-calorie diet. Changes in glycemic and non-glycemic parameters were evaluated in 12 weeks. Results: SN improves glycemic control without correction of the background antidiabetic therapy. Thus, the treatment group demonstrated a decrease in HbA1c from 7.8 ± 1.6 to 6.7 ± 1.1%, fasting glycemia - from 7.5 ± 1.2 to 5.9 ± 0.6 mmol/l, postprandial glucose (PPG) - from 10.6 ± 1.0 to 7.5 ± 0.5 mmol /l, glycemic variability SD - from 2.0 ± 0.8 to 1.1 ± 0.6 mmol/l, and normalization of glycemic pattern (p < 0.05). SN contributed to improvement of the lipid profile (p < 0.05). Conclusions: SN in patients with type 2 diabetes and visceral obesity is associated with positive dynamics of metabolic parameters. Elimination of postprandial hyperglycemia induces a decrease in glycemic variability, minimizing the progression of type 2 diabetes. |
| first_indexed | 2024-04-09T16:42:32Z |
| format | Article |
| id | doaj.art-99f4a62c3484493297e83381145e4493 |
| institution | Directory Open Access Journal |
| issn | 2079-701X 2658-5790 |
| language | Russian |
| last_indexed | 2024-04-09T16:42:32Z |
| publishDate | 2016-12-01 |
| publisher | Remedium Group LLC |
| record_format | Article |
| series | Медицинский совет |
| spelling | doaj.art-99f4a62c3484493297e83381145e44932023-04-23T06:56:38ZrusRemedium Group LLCМедицинский совет2079-701X2658-57902016-12-010310611110.21518/2079-701X-2016-3-106-11168The role and place of adequate nutrition in optimizing management of diabetes mellitus type 2А. S. Ametov0L. L. Kamynina1N. A. Chernikova2M. A. Dzhusoeva3Russian Medical Academy of Postgraduate EducationRussian Medical Academy of Postgraduate EducationRussian Medical Academy of Postgraduate EducationRussian Medical Academy of Postgraduate EducationInadequate nutrition prevents patients with type 2 diabetes (T2DM) from achieving target values of glycemic and non-glycemic parameters. Aim: to evaluate metabolic effects of the balanced diet including specialized nutrition (SN). Material and methods: the randomized clinical trial included 60 patients with type 2 diabetes treated with a double combination metformin + glibenclamide, who were divided into 2 groups. Patients in the treatment group received SN Glucerna SR which replaced the main meal; the comparison group of patients were on a natural low-calorie diet. Changes in glycemic and non-glycemic parameters were evaluated in 12 weeks. Results: SN improves glycemic control without correction of the background antidiabetic therapy. Thus, the treatment group demonstrated a decrease in HbA1c from 7.8 ± 1.6 to 6.7 ± 1.1%, fasting glycemia - from 7.5 ± 1.2 to 5.9 ± 0.6 mmol/l, postprandial glucose (PPG) - from 10.6 ± 1.0 to 7.5 ± 0.5 mmol /l, glycemic variability SD - from 2.0 ± 0.8 to 1.1 ± 0.6 mmol/l, and normalization of glycemic pattern (p < 0.05). SN contributed to improvement of the lipid profile (p < 0.05). Conclusions: SN in patients with type 2 diabetes and visceral obesity is associated with positive dynamics of metabolic parameters. Elimination of postprandial hyperglycemia induces a decrease in glycemic variability, minimizing the progression of type 2 diabetes.https://www.med-sovet.pro/jour/article/view/68сахарный диабет 2-го типаспециализированное медицинское питаниепостпрандиальная гипергликемиявариабельность гликемииtype 2 diabetesspecialized nutritionpostprandial hyperglycemiaglycemic variability |
| spellingShingle | А. S. Ametov L. L. Kamynina N. A. Chernikova M. A. Dzhusoeva The role and place of adequate nutrition in optimizing management of diabetes mellitus type 2 Медицинский совет сахарный диабет 2-го типа специализированное медицинское питание постпрандиальная гипергликемия вариабельность гликемии type 2 diabetes specialized nutrition postprandial hyperglycemia glycemic variability |
| title | The role and place of adequate nutrition in optimizing management of diabetes mellitus type 2 |
| title_full | The role and place of adequate nutrition in optimizing management of diabetes mellitus type 2 |
| title_fullStr | The role and place of adequate nutrition in optimizing management of diabetes mellitus type 2 |
| title_full_unstemmed | The role and place of adequate nutrition in optimizing management of diabetes mellitus type 2 |
| title_short | The role and place of adequate nutrition in optimizing management of diabetes mellitus type 2 |
| title_sort | role and place of adequate nutrition in optimizing management of diabetes mellitus type 2 |
| topic | сахарный диабет 2-го типа специализированное медицинское питание постпрандиальная гипергликемия вариабельность гликемии type 2 diabetes specialized nutrition postprandial hyperglycemia glycemic variability |
| url | https://www.med-sovet.pro/jour/article/view/68 |
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