Central neuraxial blockade in chronic immune thrombocytopenic purpura: Platelet count or function and the concept of rebalanced hemostasis

Anesthetic management of patients having immune thrombocytopenic purpura (ITP) remains a challenge for the anesthesiologist. Surgeries such as knee arthroplasty are associated with significant bleeding. Neuraxial anesthesia is often preferred for knee arthroplasty. However, in patients with bleeding...

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Main Authors: Tasneem Dhansura, Nabila Shaikh, Tarana Shaikh, Mohtasib Madaoo
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:The Indian Anaesthetists' Forum
Subjects:
Online Access:http://www.theiaforum.org/article.asp?issn=0973-0311;year=2016;volume=17;issue=2;spage=48;epage=51;aulast=Dhansura
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author Tasneem Dhansura
Nabila Shaikh
Tarana Shaikh
Mohtasib Madaoo
author_facet Tasneem Dhansura
Nabila Shaikh
Tarana Shaikh
Mohtasib Madaoo
author_sort Tasneem Dhansura
collection DOAJ
description Anesthetic management of patients having immune thrombocytopenic purpura (ITP) remains a challenge for the anesthesiologist. Surgeries such as knee arthroplasty are associated with significant bleeding. Neuraxial anesthesia is often preferred for knee arthroplasty. However, in patients with bleeding diathesis such as ITP, neuraxial anesthetic management remains controversial as there are no specific guidelines, and there is a risk of spinal hematoma. There are numerous case reports of safe regional anesthesia administered in parturients suffering from thrombocytopenia, but no explanation has been given. A new emerging concept of "rebalanced hemostasis" is now being used to explain the discrepancies observed in the laboratory reports versus the actual bleeding. In our case report, we have reviewed the literature and described the anesthetic management of a patient having chronic ITP and chronic obstructive pulmonary disease undergoing knee arthroplasty under neuraxial technique.
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spelling doaj.art-99f58a69b12c477b9db17c2e79ed39612022-12-22T00:42:45ZengWolters Kluwer Medknow PublicationsThe Indian Anaesthetists' Forum0973-03110973-03112016-01-01172485110.4103/0973-0311.195961Central neuraxial blockade in chronic immune thrombocytopenic purpura: Platelet count or function and the concept of rebalanced hemostasisTasneem DhansuraNabila ShaikhTarana ShaikhMohtasib MadaooAnesthetic management of patients having immune thrombocytopenic purpura (ITP) remains a challenge for the anesthesiologist. Surgeries such as knee arthroplasty are associated with significant bleeding. Neuraxial anesthesia is often preferred for knee arthroplasty. However, in patients with bleeding diathesis such as ITP, neuraxial anesthetic management remains controversial as there are no specific guidelines, and there is a risk of spinal hematoma. There are numerous case reports of safe regional anesthesia administered in parturients suffering from thrombocytopenia, but no explanation has been given. A new emerging concept of "rebalanced hemostasis" is now being used to explain the discrepancies observed in the laboratory reports versus the actual bleeding. In our case report, we have reviewed the literature and described the anesthetic management of a patient having chronic ITP and chronic obstructive pulmonary disease undergoing knee arthroplasty under neuraxial technique.http://www.theiaforum.org/article.asp?issn=0973-0311;year=2016;volume=17;issue=2;spage=48;epage=51;aulast=DhansuraBleeding diathesiscentral neuraxial blockadechronic immune thrombocytopenic purpuraepidural hematomarebalanced hemostasis
spellingShingle Tasneem Dhansura
Nabila Shaikh
Tarana Shaikh
Mohtasib Madaoo
Central neuraxial blockade in chronic immune thrombocytopenic purpura: Platelet count or function and the concept of rebalanced hemostasis
The Indian Anaesthetists' Forum
Bleeding diathesis
central neuraxial blockade
chronic immune thrombocytopenic purpura
epidural hematoma
rebalanced hemostasis
title Central neuraxial blockade in chronic immune thrombocytopenic purpura: Platelet count or function and the concept of rebalanced hemostasis
title_full Central neuraxial blockade in chronic immune thrombocytopenic purpura: Platelet count or function and the concept of rebalanced hemostasis
title_fullStr Central neuraxial blockade in chronic immune thrombocytopenic purpura: Platelet count or function and the concept of rebalanced hemostasis
title_full_unstemmed Central neuraxial blockade in chronic immune thrombocytopenic purpura: Platelet count or function and the concept of rebalanced hemostasis
title_short Central neuraxial blockade in chronic immune thrombocytopenic purpura: Platelet count or function and the concept of rebalanced hemostasis
title_sort central neuraxial blockade in chronic immune thrombocytopenic purpura platelet count or function and the concept of rebalanced hemostasis
topic Bleeding diathesis
central neuraxial blockade
chronic immune thrombocytopenic purpura
epidural hematoma
rebalanced hemostasis
url http://www.theiaforum.org/article.asp?issn=0973-0311;year=2016;volume=17;issue=2;spage=48;epage=51;aulast=Dhansura
work_keys_str_mv AT tasneemdhansura centralneuraxialblockadeinchronicimmunethrombocytopenicpurpuraplateletcountorfunctionandtheconceptofrebalancedhemostasis
AT nabilashaikh centralneuraxialblockadeinchronicimmunethrombocytopenicpurpuraplateletcountorfunctionandtheconceptofrebalancedhemostasis
AT taranashaikh centralneuraxialblockadeinchronicimmunethrombocytopenicpurpuraplateletcountorfunctionandtheconceptofrebalancedhemostasis
AT mohtasibmadaoo centralneuraxialblockadeinchronicimmunethrombocytopenicpurpuraplateletcountorfunctionandtheconceptofrebalancedhemostasis