Imbalanced frequencies of Th17 and Treg cells in acute coronary syndromes are mediated by IL-6-STAT3 signaling.
AIMS: Extensive evidence suggests inflammatory components participate in the pathogenic processes of acute coronary syndromes (ACS). In this study, we aimed to elucidate the role and mechanism underlying the imbalance of Th17 and Treg cell peripheral populations in the pathogenesis of ACS. METHODS A...
Main Authors: | Yanhui Ma, Xiangliang Yuan, Lin Deng, Weiping Xu, Yingxia Zheng, Chaoyan Yue, Guanghui Zhang, Fang Xie, Yuan H Yang, Michael P Gantier, JunPing Liu, Dakang Xu, Lisong Shen |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3753235?pdf=render |
Similar Items
-
The Dynamics of Treg/Th17 and the Imbalance of Treg/Th17 in Clonorchis sinensis-Infected Mice.
by: Chao Yan, et al.
Published: (2015-01-01) -
Treg/IL-17 ratio and Treg differentiation in patients with COPD.
by: Yang Jin, et al.
Published: (2014-01-01) -
Suppressive IL-17A+Foxp3+ and ex-Th17 IL-17AnegFoxp3+ Treg cells are a source of tumour-associated Treg cells
by: Stephanie Downs-Canner, et al.
Published: (2017-03-01) -
Breast cancer tumor microenvironment affects Treg/IL-17-producing Treg/Th17 cell axis: Molecular and therapeutic perspectives
by: Farhad Seif, et al.
Published: (2023-03-01) -
Neobaicalein Inhibits Th17 Cell Differentiation Resulting in Recovery of Th17/Treg Ratio through Blocking STAT3 Signaling Activation
by: Jian-Yu Chen, et al.
Published: (2022-12-01)