Phenolic, nutritional and molecular interaction study among different millet varieties
Millet varieties were analyzed for nutritional, antinutritional, mineral and phenolic profiles. Inhibition potential of phenolic acids for enzyme inhibition ,activity was estimated, alongside starch digestibility of millet grains was evaluated. Finger millet was found to have high contents of Ca, Mn...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-10-01
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| Series: | Food Chemistry Advances |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772753X22001381 |
| _version_ | 1797796066516533248 |
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| author | Giridhar Goudar Munikumar Manne G.J. Sathisha Paras Sharma Thirupathi Reddy Mokalla Shashi Bhushan Kumar Ouliana Ziouzenkova |
| author_facet | Giridhar Goudar Munikumar Manne G.J. Sathisha Paras Sharma Thirupathi Reddy Mokalla Shashi Bhushan Kumar Ouliana Ziouzenkova |
| author_sort | Giridhar Goudar |
| collection | DOAJ |
| description | Millet varieties were analyzed for nutritional, antinutritional, mineral and phenolic profiles. Inhibition potential of phenolic acids for enzyme inhibition ,activity was estimated, alongside starch digestibility of millet grains was evaluated. Finger millet was found to have high contents of Ca, Mn and Cu minerals. Proso and pearl millet had high protein content, whereas kodo and foxtail millet contained high content of dietary fiber. Phytic acid was comparatively higher in kodo millet, whereas oxalic acid and total tannin content was abundant in finger millet. Total phenolic content and total flavonoid content in bound phenolic fractions were comparatively higher than the free phenolic fractions and total anthocyanin content was found highest in finger millet followed by kodo and pearl millet. The millet varieties showed optimum antioxidant potential studied through different assay methods. Ferulic acid was predominantly found among all the millets in bound fraction of phenolic extract. Furthermore, phenolic acids were used to investigate different docking techniques with α-amylase, α-glucosidase, and leptin receptor enzymes. Docking studies revealed, chlorogenic acid had a high docking score and a high binding affinity against α-amylase, α-glucosidase, and leptin receptor enzymes. |
| first_indexed | 2024-03-13T03:27:32Z |
| format | Article |
| id | doaj.art-99fb00ecdca341fe90b9ca2c04585c7b |
| institution | Directory Open Access Journal |
| issn | 2772-753X |
| language | English |
| last_indexed | 2024-03-13T03:27:32Z |
| publishDate | 2023-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Food Chemistry Advances |
| spelling | doaj.art-99fb00ecdca341fe90b9ca2c04585c7b2023-06-25T04:44:25ZengElsevierFood Chemistry Advances2772-753X2023-10-012100150Phenolic, nutritional and molecular interaction study among different millet varietiesGiridhar Goudar0Munikumar Manne1G.J. Sathisha2Paras Sharma3Thirupathi Reddy Mokalla4Shashi Bhushan Kumar5Ouliana Ziouzenkova6Department of Biochemistry, Kuvempu University, Shimoga, Karnataka, India; Food Quality Analysis & Biochemistry Division, Biochem Research & Testing Laboratory, Dharwad, Karnataka, India; Corresponding authors.Clinical Division, ICMR-National Institute of Nutrition, Hyderabad, Telangana State, India; Corresponding authors.Department of Biochemistry, Kuvempu University, Shimoga, Karnataka, IndiaFood Chemistry Division, ICMR-National Institute of Nutrition, Hyderabad, Telangana State, India; Department of Food Technology, Mizoram University, Aizawl, Mizoram, IndiaNutrition Information, Communication & Health Education (NICHE) Division, ICMR-National Institute of Nutrition, Hyderabad, Telangana State, IndiaDepartment of Human Sciences, The Ohio State University, Columbus, OH 43210, United States of AmericaDepartment of Human Sciences, The Ohio State University, Columbus, OH 43210, United States of AmericaMillet varieties were analyzed for nutritional, antinutritional, mineral and phenolic profiles. Inhibition potential of phenolic acids for enzyme inhibition ,activity was estimated, alongside starch digestibility of millet grains was evaluated. Finger millet was found to have high contents of Ca, Mn and Cu minerals. Proso and pearl millet had high protein content, whereas kodo and foxtail millet contained high content of dietary fiber. Phytic acid was comparatively higher in kodo millet, whereas oxalic acid and total tannin content was abundant in finger millet. Total phenolic content and total flavonoid content in bound phenolic fractions were comparatively higher than the free phenolic fractions and total anthocyanin content was found highest in finger millet followed by kodo and pearl millet. The millet varieties showed optimum antioxidant potential studied through different assay methods. Ferulic acid was predominantly found among all the millets in bound fraction of phenolic extract. Furthermore, phenolic acids were used to investigate different docking techniques with α-amylase, α-glucosidase, and leptin receptor enzymes. Docking studies revealed, chlorogenic acid had a high docking score and a high binding affinity against α-amylase, α-glucosidase, and leptin receptor enzymes.http://www.sciencedirect.com/science/article/pii/S2772753X22001381MilletAntinutrientDigestibilityPhenolicMolecular dockingNutrient |
| spellingShingle | Giridhar Goudar Munikumar Manne G.J. Sathisha Paras Sharma Thirupathi Reddy Mokalla Shashi Bhushan Kumar Ouliana Ziouzenkova Phenolic, nutritional and molecular interaction study among different millet varieties Food Chemistry Advances Millet Antinutrient Digestibility Phenolic Molecular docking Nutrient |
| title | Phenolic, nutritional and molecular interaction study among different millet varieties |
| title_full | Phenolic, nutritional and molecular interaction study among different millet varieties |
| title_fullStr | Phenolic, nutritional and molecular interaction study among different millet varieties |
| title_full_unstemmed | Phenolic, nutritional and molecular interaction study among different millet varieties |
| title_short | Phenolic, nutritional and molecular interaction study among different millet varieties |
| title_sort | phenolic nutritional and molecular interaction study among different millet varieties |
| topic | Millet Antinutrient Digestibility Phenolic Molecular docking Nutrient |
| url | http://www.sciencedirect.com/science/article/pii/S2772753X22001381 |
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