Decreased Levels of GSH Are Associated with Platinum Resistance in High-Grade Serous Ovarian Cancer

Decreased Levels of GSH Are Associated with Platinum Resistance in High-Grade Serous Ovarian Cancer

High-grade serous ovarian cancer (HGSOC) is the most common and aggressive OC histotype. Although initially sensitive to standard platinum-based chemotherapy, most HGSOC patients relapse and become chemoresistant. We have previously demonstrated that platinum resistance is driven by a metabolic shif...

书目详细资料
Main Authors:	Daniela Criscuolo, Rosario Avolio, Matteo Parri, Simona Romano, Paola Chiarugi, Danilo Swann Matassa, Franca Esposito
格式:	文件
语言:	English
出版:	MDPI AG 2022-08-01
丛编:	Antioxidants
主题:	ovarian cancer platinum resistance GSH reactive oxygen species (ROS)
在线阅读:	https://www.mdpi.com/2076-3921/11/8/1544

相似书籍

Diverse roles of low-molecular weight thiol GSH in Francisella’s virulence, location sensing and GSH-stealing from host
由: Monique L. van Hoek, et al.
出版: (2024-01-01)

Platinum Resistance in Ovarian Cancer: Limitations of PFI Binary Classification and Potential Improvements
由: Xiaoyu LI, et al.
出版: (2024-10-01)

Circulating serum miRNAs predict response to platinum chemotherapy in high‐grade serous ovarian cancer
由: Kazuhiro Suzuki, et al.
出版: (2024-11-01)

Immunohistochemical parameters of serous ovarian carcinomas and possible mechanism of development of resistance to platinum-based drugs
由: G. V. Zhukova, et al.
出版: (2024-09-01)

Comparison of Weekly Paclitaxel Regimens in Recurrent Platinum-Resistant Ovarian Cancer: A Single Institution Retrospective Study
由: Laurence Morin, et al.
出版: (2024-08-01)

CONSEQUENCES OF AD LIBITUM ALUMINIUM ADMINISTRATION DURING THREE GENERATIONS ON RATS BLOOD GSH DINAMICS
由: CORINA GRĂVILĂ, et al.
出版: (2023-11-01)

Survival Analysis of Ovarian Carcinosarcomas Depending on Platinum or Doxorubicin Based Adjuvant Chemotherapy
由: İlker Selçuk, et al.
出版: (2015-04-01)

Clinical Impact of Olaparib for Platinum-Sensitive Recurrent Ovarian Cancer
由: Hiroaki Ishida, et al.
出版: (2025-02-01)

18F‐Fluoro‐2‐Deoxyglucose Positron Emission Tomography/Computed Tomography Measures of Spatial Heterogeneity for Predicting Platinum Resistance of High‐Grade Serous Ovarian Cancer
由: Xin Zhang, et al.
出版: (2024-10-01)

The Quantitative Indices of ERCC1 Expression in Serous Ovarian Cancer Tissue and the Efficacy of First-Line Platinum-Based Chemotherapy
由: T. A. Bogush, et al.
出版: (2020-05-01)

Combined radiomics-clinical model to predict platinum-sensitivity in advanced high-grade serous ovarian carcinoma using multimodal MRI
由: Inye Na, et al.
出版: (2024-01-01)

A nomogram to predict platinum-sensitivity and survival outcome in women with advanced epithelial ovarian cancer
由: Tsung-Hsin Yeh, et al.
出版: (2024-09-01)

Ovarian cancer ascites confers platinum chemoresistance to ovarian cancer cells
由: Yifat Koren Carmi, et al.
出版: (2024-06-01)

Cytoreductive surgery is feasible in patients with limited regional platinum-resistant recurrent ovarian cancer
由: Ruoyao Zou, et al.
出版: (2023-11-01)

Ojeok-san enhances platinum sensitivity in ovarian cancer by regulating adipocyte paracrine IGF1 secretion
由: Jiong Ma, et al.
出版: (2024-12-01)

Clinicopathological and Functional Evaluation Reveal NBS1 as a Predictor of Platinum Resistance in Epithelial Ovarian Cancers
由: Adel Alblihy, et al.
出版: (2021-01-01)

Evolving treatment paradigms for platinum-resistant ovarian cancer: An update narrative review
由: Hao Lin, et al.
出版: (2024-07-01)

Logam-logam platinum/
由: 237959 Misliah Masari

The leadership of topotecan in the treatment of recurrent platinum-resistant ovarian cancer
由: K. E. Borisov
出版: (2014-07-01)

Research advances in platinum resistance and its treatment in ovarian cancer
由: LIU Yan, HUANG Li
出版: (2024-10-01)

ADC: a deadly killer of platinum resistant ovarian cancer
由: Xu Cheng, et al.
出版: (2024-10-01)

Case report: Response to everolimus in a patient with platinum resistant, high grade serous ovarian carcinoma with biallelic TSC2 inactivation
由: Mariko Peterson, et al.
出版: (2024-03-01)

CuFeS2 nanozyme regulating ROS/GSH redox induces ferroptosis-like death in bacteria for robust anti-infection therapy
由: Huidong Wang, et al.
出版: (2024-03-01)

Polydatin-Induced Shift of Redox Balance and Its Anti-Cancer Impact on Human Osteosarcoma Cells
由: Alessio Cimmino, et al.
出版: (2024-12-01)

Platinum desensitization therapy and its impact on the prognosis of ovary high-grade serous adenocarcinoma: a real world-data
由: Kemin Li, et al.
出版: (2024-01-01)

GSH and Ferroptosis: Side-by-Side Partners in the Fight against Tumors
由: Yulang Jiang, et al.
出版: (2024-06-01)

Bevacizumab combined with platinum-based chemotherapy in primary or relapsed ovarian cancer patients: Meta-analysis and literature to review
由: Abubakar Tauseef, et al.
出版: (2023-11-01)

Bioinformatic profiling identifies a platinum‐resistant–related risk signature for ovarian cancer
由: Ce Wu, et al.
出版: (2020-02-01)

Platinum metals review
出版: ([19-)

Efficacy and safety of low‐dose apatinib in ovarian cancer patients with platinum‐resistance or platinum‐refractoriness: A single‐center retrospective study
由: Wei Chen, et al.
出版: (2020-08-01)

Efficacy of a platinum-based chemotherapy rechallenge for platinum-sensitive recurrence after PARP inhibitor maintenance
由: Takehiro Nakao, et al.
出版: (2024-10-01)

Cysteine and homocysteine can be exploited by GPX4 in ferroptosis inhibition independent of GSH synthesis
由: Chaoyi Xia, et al.
出版: (2024-02-01)

pH/GSH dual-responsive nanoparticle for auto-amplified tumor therapy of breast cancer
由: Shengnan Huang, et al.
出版: (2024-06-01)

NaHS immersion alleviates the stress effect of chromium(III) on alfalfa seeds by affecting active oxygen metabolism
由: Ting Bu, et al.
出版: (2024-12-01)

CDK6 protects epithelial ovarian cancer from platinum‐induced death via FOXO3 regulation
由: Alessandra Dall'Acqua, et al.
出版: (2017-08-01)

Determination of platinum-resistance of women with ovarian cancer by FTIR spectroscopy combined with multivariate analyses and machine learning methods
由: Marta Kluz-Barłowska, et al.
出版: (2024-10-01)

Ovarian cancer: new accents treatment of patients with platinum-sensitive relapses
由: A. G. Kedrova, et al.
出版: (2016-11-01)

Induction of circulating ABCB1 transcripts under platinum-based chemotherapy indicates poor prognosis and a bone micrometastatic phenotype in ovarian cancer patients
由: Franziska Maria Schwarz, et al.
出版: (2024-08-01)

Targeting autophagy in platinum-sensitive relapsed ovarian cancer: randomized phase II trial of hydroxychloroquine with chemotherapy with biomarker correlation
由: Luxitaa Goenka, et al.
出版: (2025-02-01)

Segregation of impurities in platinum and platinum-based alloys
由: Trumić Biserka, et al.
出版: (2015-01-01)