The Genetics of Leber’s Hereditary Optic Neuropathy: A Literature Review
Leber’s hereditary optic neuropathy (LHON) is a mitochondrial disease characterized by a painless, acute loss of central vision, with 95% of affected individuals harbouring one of three pathogenic mutations (G11778GA, G3460A, or T14484C). The purpose of this review is to highlight the distinguishing...
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| Format: | Article |
| Language: | English |
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University of Ottawa
2018-11-01
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| Series: | University of Ottawa Journal of Medicine |
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| Online Access: | https://uottawa.scholarsportal.info/ottawa/index.php/uojm-jmuo/article/view/3846 |