Oncocytic adrenocortical neoplasm of borderline uncertain malignant potential diagnosed after robot-assisted adrenalectomy case report
Abstract Background Adrenal incidentalomas are radiologically discovered tumors that represent a variety of pathologies, with the diagnosis clinched only on surgical pathology. These tumors may be clinically monitored, but triggers for surgery include size > 4 cm, concerning features on radiology...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-04-01
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| Series: | BMC Urology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12894-023-01238-1 |
| _version_ | 1797845757798121472 |
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| author | Chih Peng Chin Ralph Grauer Burak Ucpinar Mani Menon Qiusheng Si Ketan K. Badani |
| author_facet | Chih Peng Chin Ralph Grauer Burak Ucpinar Mani Menon Qiusheng Si Ketan K. Badani |
| author_sort | Chih Peng Chin |
| collection | DOAJ |
| description | Abstract Background Adrenal incidentalomas are radiologically discovered tumors that represent a variety of pathologies, with the diagnosis clinched only on surgical pathology. These tumors may be clinically monitored, but triggers for surgery include size > 4 cm, concerning features on radiology, or hormonally functioning. Adrenal oncocytic neoplasms (AONs) are notably rare and typically nonfunctional tumors that are discovered as incidentalomas and exist on a spectrum of malignant potential. Case presentation We discovered an exceptionally large (15 cm in the greatest dimension) incidentaloma in a 73-year-old man with left back pain and he was treated with robotic-assisted adrenalectomy. Surgical pathology was consistent with AON of borderline uncertain malignant potential; adjuvant mitotane and radiation were omitted based on shared decision-making. Conclusion Large AONs are rare, usually benign tumors that can be safely treated with robotic-assisted adrenalectomy. Surgical pathology is the crux of diagnosis and post-operative management, as it informs both the initiation of adjuvant therapy and the stringency of post-operative surveillance. |
| first_indexed | 2024-04-09T17:44:05Z |
| format | Article |
| id | doaj.art-99fcc36afd4f4193be22c3a5fbeac103 |
| institution | Directory Open Access Journal |
| issn | 1471-2490 |
| language | English |
| last_indexed | 2024-04-09T17:44:05Z |
| publishDate | 2023-04-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Urology |
| spelling | doaj.art-99fcc36afd4f4193be22c3a5fbeac1032023-04-16T11:26:15ZengBMCBMC Urology1471-24902023-04-012311410.1186/s12894-023-01238-1Oncocytic adrenocortical neoplasm of borderline uncertain malignant potential diagnosed after robot-assisted adrenalectomy case reportChih Peng Chin0Ralph Grauer1Burak Ucpinar2Mani Menon3Qiusheng Si4Ketan K. Badani5Department of Urology, Icahn School of Medicine at Mount SinaiDepartment of Urology, Icahn School of Medicine at Mount SinaiDepartment of Urology, Icahn School of Medicine at Mount SinaiDepartment of Urology, Icahn School of Medicine at Mount SinaiDepartment of Pathology, Icahn School of Medicine at Mount SinaiDepartment of Urology, Icahn School of Medicine at Mount SinaiAbstract Background Adrenal incidentalomas are radiologically discovered tumors that represent a variety of pathologies, with the diagnosis clinched only on surgical pathology. These tumors may be clinically monitored, but triggers for surgery include size > 4 cm, concerning features on radiology, or hormonally functioning. Adrenal oncocytic neoplasms (AONs) are notably rare and typically nonfunctional tumors that are discovered as incidentalomas and exist on a spectrum of malignant potential. Case presentation We discovered an exceptionally large (15 cm in the greatest dimension) incidentaloma in a 73-year-old man with left back pain and he was treated with robotic-assisted adrenalectomy. Surgical pathology was consistent with AON of borderline uncertain malignant potential; adjuvant mitotane and radiation were omitted based on shared decision-making. Conclusion Large AONs are rare, usually benign tumors that can be safely treated with robotic-assisted adrenalectomy. Surgical pathology is the crux of diagnosis and post-operative management, as it informs both the initiation of adjuvant therapy and the stringency of post-operative surveillance.https://doi.org/10.1186/s12894-023-01238-1Adrenal oncocytic tumorOncocytomaGenitourinary neoplasmRobotic surgeryOncology |
| spellingShingle | Chih Peng Chin Ralph Grauer Burak Ucpinar Mani Menon Qiusheng Si Ketan K. Badani Oncocytic adrenocortical neoplasm of borderline uncertain malignant potential diagnosed after robot-assisted adrenalectomy case report BMC Urology Adrenal oncocytic tumor Oncocytoma Genitourinary neoplasm Robotic surgery Oncology |
| title | Oncocytic adrenocortical neoplasm of borderline uncertain malignant potential diagnosed after robot-assisted adrenalectomy case report |
| title_full | Oncocytic adrenocortical neoplasm of borderline uncertain malignant potential diagnosed after robot-assisted adrenalectomy case report |
| title_fullStr | Oncocytic adrenocortical neoplasm of borderline uncertain malignant potential diagnosed after robot-assisted adrenalectomy case report |
| title_full_unstemmed | Oncocytic adrenocortical neoplasm of borderline uncertain malignant potential diagnosed after robot-assisted adrenalectomy case report |
| title_short | Oncocytic adrenocortical neoplasm of borderline uncertain malignant potential diagnosed after robot-assisted adrenalectomy case report |
| title_sort | oncocytic adrenocortical neoplasm of borderline uncertain malignant potential diagnosed after robot assisted adrenalectomy case report |
| topic | Adrenal oncocytic tumor Oncocytoma Genitourinary neoplasm Robotic surgery Oncology |
| url | https://doi.org/10.1186/s12894-023-01238-1 |
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