Rad1 attenuates DNA double-strand breaks and cell cycle arrest in type II alveolar epithelial cells of rats with bronchopulmonary dysplasia

Rad1 attenuates DNA double-strand breaks and cell cycle arrest in type II alveolar epithelial cells of rats with bronchopulmonary dysplasia

Abstract Background Bronchopulmonary dysplasia (BPD) is the most common and serious chronic lung disease in preterm infants with pathological characteristics of arrested lung development. DNA double-strand breaks (DSBs) are a serious manifestation of oxidative stress damage, but little is known abou...

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Bibliographic Details
Main Authors: Xin Tong, Danni Li, Na Liu, Wanjie Huang, Xinyi Zhao, Dan Zhang, Xindong Xue, Jianhua Fu
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Molecular Medicine
Subjects:
Bronchopulmonary dysplasia
Arrested lung development
DNA double-strand breaks
Rad1
Cell cycle arrest
Online Access:https://doi.org/10.1186/s10020-023-00660-3

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