Hypoxia‐induced YAP activation and focal adhesion turnover to promote cell migration in mesenchymal TNBC cells

Hypoxia‐induced YAP activation and focal adhesion turnover to promote cell migration in mesenchymal TNBC cells

Abstract Background Hypoxia is commonly characterized by malignant tumors that promote the aggressiveness and metastatic potential of cancer. Triple‐negative breast cancer (TNBC) is the most aggressive subtype of breast cancer, with approximately 46% capacity related to distant metastasis. Transcrip...

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Bibliographic Details
Main Authors: Thi My Hang Nguyen, Yi‐Shyun Lai, Ying‐Chi Chen, Tzu‐Chien Lin, Ngoc Thang Nguyen, Wen‐Tai Chiu
Format: Article
Language:English
Published: Wiley 2023-04-01
Series:Cancer Medicine
Subjects:
cell migration
focal adhesions
hypoxia
mesenchymal TNBC
YAP
Online Access:https://doi.org/10.1002/cam4.5680

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