Effect of Obesity on the Respiratory Parameters in Children with Obstructive Sleep Apnea Syndrome
The aim of the study was to investigate how obesity can influence sleep respiratory parameters in obstructive sleep apnea syndrome (OSAS) in children. Methods: The study analyzes 56 Caucasian children and adolescents aged 11 ± 2.79 years with a BMI > 5th percentiles and a PSQ value ≥ 0.33. Childr...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-11-01
|
| Series: | Children |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2227-9067/10/12/1874 |
| _version_ | 1797381607900839936 |
|---|---|
| author | Carolina Caliendo Rossella Femiano Giuseppina Rosaria Umano Stefano Martina Ludovica Nucci Letizia Perillo Vincenzo Grassia |
| author_facet | Carolina Caliendo Rossella Femiano Giuseppina Rosaria Umano Stefano Martina Ludovica Nucci Letizia Perillo Vincenzo Grassia |
| author_sort | Carolina Caliendo |
| collection | DOAJ |
| description | The aim of the study was to investigate how obesity can influence sleep respiratory parameters in obstructive sleep apnea syndrome (OSAS) in children. Methods: The study analyzes 56 Caucasian children and adolescents aged 11 ± 2.79 years with a BMI > 5th percentiles and a PSQ value ≥ 0.33. Children were divided into Obesity Group (OG) with BMI ≥ 95th and Control Group (CG) with 5th < BMI > 95th percentile. All selected children underwent PG. Respiratory parameters AHI (Apnea–Hypopnea Index), SaO<sub>2</sub> (Saturation of Oxygen), ODI (Oxygen Desaturation Index), and Nadir (the lowest value of SaO<sub>2</sub> registered during PG) were extracted from the PG. AHI was used to divide the severity of OSAS into four levels: snoring (AHI ≤ 1), mild (AHI > 1 and ≤5), moderate (AHI > 5 and <10), and severe (AHI ≥ 10). Results: The comparison analysis between the OG and CG showed a statistical significance only for ODI (<i>p</i> = 0.02). A statistically significant correlation between BMI and AHI (r = 0.02), SaO<sub>2</sub> (r = 0.01), and Nadir O<sub>2</sub> (r = 0.02) was found. Conclusions: There was no strong correlation between obesity and OSAS, but a positive association was found between BMI and AHI severity. |
| first_indexed | 2024-03-08T20:53:53Z |
| format | Article |
| id | doaj.art-9a00b11029d84794966137d17df40697 |
| institution | Directory Open Access Journal |
| issn | 2227-9067 |
| language | English |
| last_indexed | 2024-03-08T20:53:53Z |
| publishDate | 2023-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Children |
| spelling | doaj.art-9a00b11029d84794966137d17df406972023-12-22T14:00:21ZengMDPI AGChildren2227-90672023-11-011012187410.3390/children10121874Effect of Obesity on the Respiratory Parameters in Children with Obstructive Sleep Apnea SyndromeCarolina Caliendo0Rossella Femiano1Giuseppina Rosaria Umano2Stefano Martina3Ludovica Nucci4Letizia Perillo5Vincenzo Grassia6Multidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania “Luigi Vanvitelli”, 80138 Naples, ItalyMultidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania “Luigi Vanvitelli”, 80138 Naples, ItalyDepartment of the Woman, the Child, and General and Specialized Surgery, University of Campania “Luigi Vanvitelli”, 80138 Naples, ItalyDepartment of Medicine, Surgery and Dentistry “Scuola Medica Salernitana”, University of Salerno, 84123 Salerno, ItalyMultidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania “Luigi Vanvitelli”, 80138 Naples, ItalyMultidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania “Luigi Vanvitelli”, 80138 Naples, ItalyMultidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania “Luigi Vanvitelli”, 80138 Naples, ItalyThe aim of the study was to investigate how obesity can influence sleep respiratory parameters in obstructive sleep apnea syndrome (OSAS) in children. Methods: The study analyzes 56 Caucasian children and adolescents aged 11 ± 2.79 years with a BMI > 5th percentiles and a PSQ value ≥ 0.33. Children were divided into Obesity Group (OG) with BMI ≥ 95th and Control Group (CG) with 5th < BMI > 95th percentile. All selected children underwent PG. Respiratory parameters AHI (Apnea–Hypopnea Index), SaO<sub>2</sub> (Saturation of Oxygen), ODI (Oxygen Desaturation Index), and Nadir (the lowest value of SaO<sub>2</sub> registered during PG) were extracted from the PG. AHI was used to divide the severity of OSAS into four levels: snoring (AHI ≤ 1), mild (AHI > 1 and ≤5), moderate (AHI > 5 and <10), and severe (AHI ≥ 10). Results: The comparison analysis between the OG and CG showed a statistical significance only for ODI (<i>p</i> = 0.02). A statistically significant correlation between BMI and AHI (r = 0.02), SaO<sub>2</sub> (r = 0.01), and Nadir O<sub>2</sub> (r = 0.02) was found. Conclusions: There was no strong correlation between obesity and OSAS, but a positive association was found between BMI and AHI severity.https://www.mdpi.com/2227-9067/10/12/1874obstructive sleep apnea syndrome (OSAS)Nocturnal Home Cardiorespiratory Polygraphy (PG)obesitySaturation O<sub>2</sub> (SaO<sub>2</sub>)Pediatric Sleep Questionnaire (PSQ) |
| spellingShingle | Carolina Caliendo Rossella Femiano Giuseppina Rosaria Umano Stefano Martina Ludovica Nucci Letizia Perillo Vincenzo Grassia Effect of Obesity on the Respiratory Parameters in Children with Obstructive Sleep Apnea Syndrome Children obstructive sleep apnea syndrome (OSAS) Nocturnal Home Cardiorespiratory Polygraphy (PG) obesity Saturation O<sub>2</sub> (SaO<sub>2</sub>) Pediatric Sleep Questionnaire (PSQ) |
| title | Effect of Obesity on the Respiratory Parameters in Children with Obstructive Sleep Apnea Syndrome |
| title_full | Effect of Obesity on the Respiratory Parameters in Children with Obstructive Sleep Apnea Syndrome |
| title_fullStr | Effect of Obesity on the Respiratory Parameters in Children with Obstructive Sleep Apnea Syndrome |
| title_full_unstemmed | Effect of Obesity on the Respiratory Parameters in Children with Obstructive Sleep Apnea Syndrome |
| title_short | Effect of Obesity on the Respiratory Parameters in Children with Obstructive Sleep Apnea Syndrome |
| title_sort | effect of obesity on the respiratory parameters in children with obstructive sleep apnea syndrome |
| topic | obstructive sleep apnea syndrome (OSAS) Nocturnal Home Cardiorespiratory Polygraphy (PG) obesity Saturation O<sub>2</sub> (SaO<sub>2</sub>) Pediatric Sleep Questionnaire (PSQ) |
| url | https://www.mdpi.com/2227-9067/10/12/1874 |
| work_keys_str_mv | AT carolinacaliendo effectofobesityontherespiratoryparametersinchildrenwithobstructivesleepapneasyndrome AT rossellafemiano effectofobesityontherespiratoryparametersinchildrenwithobstructivesleepapneasyndrome AT giuseppinarosariaumano effectofobesityontherespiratoryparametersinchildrenwithobstructivesleepapneasyndrome AT stefanomartina effectofobesityontherespiratoryparametersinchildrenwithobstructivesleepapneasyndrome AT ludovicanucci effectofobesityontherespiratoryparametersinchildrenwithobstructivesleepapneasyndrome AT letiziaperillo effectofobesityontherespiratoryparametersinchildrenwithobstructivesleepapneasyndrome AT vincenzograssia effectofobesityontherespiratoryparametersinchildrenwithobstructivesleepapneasyndrome |