Impact of Obesity on Clinical Outcomes of Patients with Intra-Abdominal Hypertension and Abdominal Compartment Syndrome
Intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) are associated with high morbidity and mortality. Obesity may result in increased intra-abdominal pressure (IAP) and affect clinical outcomes of patients with IAH and/or ACS. This study aims to establish the impact of obesit...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-01-01
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| Series: | Life |
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| Online Access: | https://www.mdpi.com/2075-1729/13/2/330 |
| _version_ | 1827756821979332608 |
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| author | Swetha Mohan Zavier Yongxuan Lim Kai Siang Chan Vishal G. Shelat |
| author_facet | Swetha Mohan Zavier Yongxuan Lim Kai Siang Chan Vishal G. Shelat |
| author_sort | Swetha Mohan |
| collection | DOAJ |
| description | Intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) are associated with high morbidity and mortality. Obesity may result in increased intra-abdominal pressure (IAP) and affect clinical outcomes of patients with IAH and/or ACS. This study aims to establish the impact of obesity on the clinical outcomes of IAH and ACS patients. A systematic search of Medline, Embase, and Scopus was performed in August 2022. Nine studies comprising 9938 patients were included. There were 65.1% males (n = 6250/9596). Patient demographics, comorbidities, and morbidities were analyzed in correlation with obesity and IAP. Obese patients had a higher risk of IAH (OR 8.5, <i>p</i> < 0.001). Obesity was associated with the need for renal replacement therapy, intensive care unit-acquired infections, systemic inflammatory response syndrome, acute respiratory distress syndrome, length of hospital stay, and mortality. This review highlights the lacunae in the existing literature to underpin the direct impact of obesity, independent of obesity-associated comorbidities, on the clinical outcomes of IAH and ACS. |
| first_indexed | 2024-03-11T08:33:47Z |
| format | Article |
| id | doaj.art-9a09ddf35c74480dbe343ff4a6cf6117 |
| institution | Directory Open Access Journal |
| issn | 2075-1729 |
| language | English |
| last_indexed | 2024-03-11T08:33:47Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Life |
| spelling | doaj.art-9a09ddf35c74480dbe343ff4a6cf61172023-11-16T21:39:46ZengMDPI AGLife2075-17292023-01-0113233010.3390/life13020330Impact of Obesity on Clinical Outcomes of Patients with Intra-Abdominal Hypertension and Abdominal Compartment SyndromeSwetha Mohan0Zavier Yongxuan Lim1Kai Siang Chan2Vishal G. Shelat3Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 308232, SingaporeLee Kong Chian School of Medicine, Nanyang Technological University, Singapore 308232, SingaporeTan Tock Seng Hospital, Singapore 308433, SingaporeTan Tock Seng Hospital, Singapore 308433, SingaporeIntra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) are associated with high morbidity and mortality. Obesity may result in increased intra-abdominal pressure (IAP) and affect clinical outcomes of patients with IAH and/or ACS. This study aims to establish the impact of obesity on the clinical outcomes of IAH and ACS patients. A systematic search of Medline, Embase, and Scopus was performed in August 2022. Nine studies comprising 9938 patients were included. There were 65.1% males (n = 6250/9596). Patient demographics, comorbidities, and morbidities were analyzed in correlation with obesity and IAP. Obese patients had a higher risk of IAH (OR 8.5, <i>p</i> < 0.001). Obesity was associated with the need for renal replacement therapy, intensive care unit-acquired infections, systemic inflammatory response syndrome, acute respiratory distress syndrome, length of hospital stay, and mortality. This review highlights the lacunae in the existing literature to underpin the direct impact of obesity, independent of obesity-associated comorbidities, on the clinical outcomes of IAH and ACS.https://www.mdpi.com/2075-1729/13/2/330abdominal compartment syndromeintra-abdominal hypertensionintra-abdominal pressureobesity |
| spellingShingle | Swetha Mohan Zavier Yongxuan Lim Kai Siang Chan Vishal G. Shelat Impact of Obesity on Clinical Outcomes of Patients with Intra-Abdominal Hypertension and Abdominal Compartment Syndrome Life abdominal compartment syndrome intra-abdominal hypertension intra-abdominal pressure obesity |
| title | Impact of Obesity on Clinical Outcomes of Patients with Intra-Abdominal Hypertension and Abdominal Compartment Syndrome |
| title_full | Impact of Obesity on Clinical Outcomes of Patients with Intra-Abdominal Hypertension and Abdominal Compartment Syndrome |
| title_fullStr | Impact of Obesity on Clinical Outcomes of Patients with Intra-Abdominal Hypertension and Abdominal Compartment Syndrome |
| title_full_unstemmed | Impact of Obesity on Clinical Outcomes of Patients with Intra-Abdominal Hypertension and Abdominal Compartment Syndrome |
| title_short | Impact of Obesity on Clinical Outcomes of Patients with Intra-Abdominal Hypertension and Abdominal Compartment Syndrome |
| title_sort | impact of obesity on clinical outcomes of patients with intra abdominal hypertension and abdominal compartment syndrome |
| topic | abdominal compartment syndrome intra-abdominal hypertension intra-abdominal pressure obesity |
| url | https://www.mdpi.com/2075-1729/13/2/330 |
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