PB1761: PRECLINICAL EVALUATION OF THE MENIN INHIBITOR ZIFTOMENIB IN PRIMARY AML SPECIMENS

PB1761: PRECLINICAL EVALUATION OF THE MENIN INHIBITOR ZIFTOMENIB IN PRIMARY AML SPECIMENS

Bibliographic Details
Main Authors:	Brett Stevens, Krysta Engel, Austin Gillen, Shanshan Pei, Anna Krug, Monica Ransom, Sarah Staggs, Francis Burrows, Blake Tomkinson, Linda Kessler, Craig Jordan, Clayton Smith
Format:	Article
Language:	English
Published:	Wiley 2023-08-01
Series:	HemaSphere
Online Access:	http://journals.lww.com/10.1097/01.HS9.0000973900.20086.99

Similar Items

Menin inhibitor ziftomenib (KO-539) synergizes with drugs targeting chromatin regulation or apoptosis and sensitizes acute myeloid leukemia with <i>MLL</i> rearrangement or <i>NPM1</i> mutation to venetoclax
by: Johanna Rausch, et al.
Published: (2023-04-01)

The MLL–Menin Interaction is a Therapeutic Vulnerability in NUP98-rearranged AML
by: Milad Rasouli, et al.
Published: (2023-08-01)

PB1885: PHASE 1 STUDY OF ZIFTOMENIB IN COMBINATION WITH VENETOCLAX, VENETOCLAX/AZACITIDINE, OR STANDARD INDUCTION (7 + 3) CHEMOTHERAPY IN PATIENTS WITH ACUTE MYELOID LEUKEMIA
by: Amer M Zeidan, et al.
Published: (2023-08-01)

S125: NON-GENETIC RESISTANCE TO MENIN INHIBITION IN AML IS REVERSIBLE BY PERTURBATION OF KAT6A
by: Florian Perner, et al.
Published: (2023-08-01)

Targeting of epigenetic co-dependencies enhances anti-AML efficacy of Menin inhibitor in AML with MLL1-r or mutant NPM1
by: Warren Fiskus, et al.
Published: (2023-04-01)

Menin@s de rua:
by: Antonio Ozaí da Silva
Published: (2021-05-01)

Pharmacokinetics and ADME Characterization After Oral and Intravenous Administration of [14C]‐Ziftomenib in Healthy Male Participants
by: Amitava Mitra, et al.
Published: (2025-02-01)

Repressing HIF-1α-induced HDAC9 contributes to the synergistic effect of venetoclax and MENIN inhibitor in KMT2Ar AML
by: Qing Ling, et al.
Published: (2023-12-01)

P504: UPDATED DATA FOR ZIFTOMENIB IN PATIENTS WITH NPM1-MUTATED RELAPSED OR REFRACTORY ACUTE MYELOID LEUKEMIA
by: Amir Fathi, et al.
Published: (2023-08-01)

FBP1 Is an Interacting Partner of Menin
by: Shadia Zaman, et al.
Published: (2014-01-01)

Investigating the novel-binding site of RPA2 on Menin and predicting the effect of point mutation of Menin through protein–protein interactions
by: Gurjeet Kaur, et al.
Published: (2023-06-01)

Menin interacts directly with the homeobox-containing protein Pem.
by: Lemmens, I, et al.
Published: (2001)

Expression of menin gene mRNA in pituitary tumours.
by: Satta, M, et al.
Published: (1999)

Exploring new horizons in menin: it’s bleximenib’s turn
by: Bradley Rockwell, et al.
Published: (2025-03-01)

Ay Tanrısı Men'in Adı ve Menşei Hakkında
by: Afif Erzen
Published: (1953-01-01)

Development of an orally bioavailable selective inhibitor of the menin-MLL
by: Hai-Jing Zhong, et al.
Published: (2023-09-01)

Investigating the Effects of Amino Acid Variations in Human Menin
by: Carmen Biancaniello, et al.
Published: (2022-03-01)

Hypothalamic Menin regulates systemic aging and cognitive decline.
by: Lige Leng, et al.
Published: (2023-03-01)

Gümülcine Ayânı Tokadcıklı Süleyman 1761(?)-1804
by: Necmettin Aygün
Published: (2010-12-01)

Multi-omics analyses of MEN1 missense mutations identify disruption of menin–MLL and menin–JunD interactions as critical requirements for molecular pathogenicity
by: Koen M. A. Dreijerink, et al.
Published: (2022-08-01)

Interaction of MLL amino terminal sequences with menin is required for transformation.
by: Caslini, C, et al.
Published: (2007)

Consequence of Menin Deficiency in Mouse Adipocytes Derived by In Vitro Differentiation
by: Vaishali I. Parekh, et al.
Published: (2015-01-01)

Design of Inhibitors That Target the Menin–Mixed-Lineage Leukemia Interaction
by: Moses N. Arthur, et al.
Published: (2023-12-01)

Loss of tumor suppressor menin expression in high grade cholangiocarcinomas
by: Terry C. Lairmore, et al.
Published: (2023-02-01)

ŠIAULIŲ „KULTŪROS“ BENDROVĖS (1920–1937) KNYGŲ MENINĖ KULTŪRA
by: EMILIJA KOŽENEVSKAJA
Published: (2014-01-01)

The menin tumor suppressor protein is phosphorylated in response to DNA damage.
by: Joshua Francis, et al.
Published: (2011-01-01)

Reanalyses of Maskelyne's tidal data at St. Helena in 1761
by: P. L. Woodworth, et al.
Published: (2022-09-01)

Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors.
by: Milne, T, et al.
Published: (2005)

Menin inhibitors for the treatment of acute myeloid leukemia: challenges and opportunities ahead
by: Kalyan V. G. Nadiminti, et al.
Published: (2024-11-01)

Menin Reduces Parvalbumin Expression and is Required for the Anti‐Depressant Function of Ketamine
by: Lige Leng, et al.
Published: (2024-02-01)

The class of 1761: Examinations, state, and elites in eighteenth-century China.
by: De Weerdt, H
Published: (2005)

The genome sequence of the Dot Moth, Melanchra persicariae (Linnaeus, 1761)
by: Boyes, D, et al.
Published: (2023)

The genome sequence of the Feathered Gothic, Tholera decimalis (Poda, 1761)
by: Boyes, D, et al.
Published: (2023)

The genome sequence of the Leopard Moth, Zeuzera pyrina (Linnaeus, 1761)
by: Boyes, D, et al.
Published: (2023)

Menin maintains lysosomal and mitochondrial homeostasis through epigenetic mechanisms in lung cancer
by: Jun-Bo Yuan, et al.
Published: (2025-03-01)

Research progress in Menin-MLL interaction and its inhibitors in MLL-rearranged leukemia
by: FANG Xinyue, et al.
Published: (2024-10-01)

Menin inhibitor MI-503 exhibits potent anti-cancer activity in osteosarcoma
by: Shen Tian, et al.
Published: (2025-02-01)

Genetic Deletion of Menin in Mouse Mesenchymal Stem Cells: An Experimental and Computational Analysis
by: Jad Abi‐Rafeh, et al.
Published: (2022-05-01)

Targeting menin: a promising therapeutic strategy for susceptible acute leukemia subtypes
by: Pietro Di Fazio
Published: (2023-10-01)

Nasopharyngeal Meningococcal Carriage among Older Adults in Türkiye (MeninGOLD Study)
by: Pinar Yildiz, et al.
Published: (2023-08-01)