Absence of ataxin-3 leads to enhanced stress response in C. elegans.

Absence of ataxin-3 leads to enhanced stress response in C. elegans.

Ataxin-3, the protein involved in Machado-Joseph disease, is able to bind ubiquitylated substrates and act as a deubiquitylating enzyme in vitro, and it has been involved in the modulation of protein degradation by the ubiquitin-proteasome pathway. C. elegans and mouse ataxin-3 knockout models are v...

书目详细资料
Main Authors:	Ana João Rodrigues, Andreia Neves-Carvalho, Andreia Teixeira-Castro, Anne Rokka, Garry Corthals, Elsa Logarinho, Patrícia Maciel
格式:	文件
语言:	English
出版:	Public Library of Science (PLoS) 2011-04-01
丛编:	PLoS ONE
在线阅读:	http://europepmc.org/articles/PMC3079722?pdf=render

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