Primary Synovial Cell Sarcoma of the Kidney: Case Report and Review of the Literature
Synovial cell sarcoma (SCS) of the kidney is a rare tumor entity with a poor prognosis. Morphologic and immunohistochemical characteristics may overlap with other more common neoplasms of the kidney. Therefore, the diagnosis of primary renal SCS not only requires the exclusion of similar tumor types...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Karger Publishers
2015-03-01
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| Series: | Case Reports in Oncology |
| Subjects: | |
| Online Access: | http://www.karger.com/Article/FullText/379740 |
| _version_ | 1818250373532483584 |
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| author | Marc Vedana Maya Fuenfschilling Alexandar Tzankov Tobias Zellweger |
| author_facet | Marc Vedana Maya Fuenfschilling Alexandar Tzankov Tobias Zellweger |
| author_sort | Marc Vedana |
| collection | DOAJ |
| description | Synovial cell sarcoma (SCS) of the kidney is a rare tumor entity with a poor prognosis. Morphologic and immunohistochemical characteristics may overlap with other more common neoplasms of the kidney. Therefore, the diagnosis of primary renal SCS not only requires the exclusion of similar tumor types, but also a confirmation of SYT-SSX gene fusion using molecular techniques. The treatment comprises radical surgery, and, depending on age and health status, adjuvant chemotherapy in selected patients. Here, we present an elderly SCS patient in whom straightforward radical surgical treatment resulted in a sustained complete remission; it allowed us to perform a literature survey focusing on current diagnostic tools for SCS. |
| first_indexed | 2024-12-12T15:51:22Z |
| format | Article |
| id | doaj.art-9a0ff1114272421c93dc93b33ab775cd |
| institution | Directory Open Access Journal |
| issn | 1662-6575 |
| language | English |
| last_indexed | 2024-12-12T15:51:22Z |
| publishDate | 2015-03-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Oncology |
| spelling | doaj.art-9a0ff1114272421c93dc93b33ab775cd2022-12-22T00:19:38ZengKarger PublishersCase Reports in Oncology1662-65752015-03-018112813210.1159/000379740379740Primary Synovial Cell Sarcoma of the Kidney: Case Report and Review of the LiteratureMarc VedanaMaya FuenfschillingAlexandar TzankovTobias ZellwegerSynovial cell sarcoma (SCS) of the kidney is a rare tumor entity with a poor prognosis. Morphologic and immunohistochemical characteristics may overlap with other more common neoplasms of the kidney. Therefore, the diagnosis of primary renal SCS not only requires the exclusion of similar tumor types, but also a confirmation of SYT-SSX gene fusion using molecular techniques. The treatment comprises radical surgery, and, depending on age and health status, adjuvant chemotherapy in selected patients. Here, we present an elderly SCS patient in whom straightforward radical surgical treatment resulted in a sustained complete remission; it allowed us to perform a literature survey focusing on current diagnostic tools for SCS.http://www.karger.com/Article/FullText/379740Renal synovial cell sarcomaRenal spindle cell tumorSYT-SSX gene fusionSYT gene rearrangementTransducin-like enhancer of split 1 |
| spellingShingle | Marc Vedana Maya Fuenfschilling Alexandar Tzankov Tobias Zellweger Primary Synovial Cell Sarcoma of the Kidney: Case Report and Review of the Literature Case Reports in Oncology Renal synovial cell sarcoma Renal spindle cell tumor SYT-SSX gene fusion SYT gene rearrangement Transducin-like enhancer of split 1 |
| title | Primary Synovial Cell Sarcoma of the Kidney: Case Report and Review of the Literature |
| title_full | Primary Synovial Cell Sarcoma of the Kidney: Case Report and Review of the Literature |
| title_fullStr | Primary Synovial Cell Sarcoma of the Kidney: Case Report and Review of the Literature |
| title_full_unstemmed | Primary Synovial Cell Sarcoma of the Kidney: Case Report and Review of the Literature |
| title_short | Primary Synovial Cell Sarcoma of the Kidney: Case Report and Review of the Literature |
| title_sort | primary synovial cell sarcoma of the kidney case report and review of the literature |
| topic | Renal synovial cell sarcoma Renal spindle cell tumor SYT-SSX gene fusion SYT gene rearrangement Transducin-like enhancer of split 1 |
| url | http://www.karger.com/Article/FullText/379740 |
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