Clinical and Epidemiological Characteristics of Mpox in HIV-Infected and Uninfected Men Who Have Sex with Men: A Retrospective Study in Lisbon

The resurgence of Mpox, predominantly among men who have sex with men (MSM), has prompted an analysis of its clinical manifestations and epidemiological patterns, particularly in individuals living with human immunodeficiency virus (HIV). This retrospective study aims to delineate and compare the cl...

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Main Authors: Diogo de Sousa, Yuliya Volovetska, Daniel Nunes, Carlos Lemos, João Borges-Costa, Paulo Filipe
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/16/2/225
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author Diogo de Sousa
Yuliya Volovetska
Daniel Nunes
Carlos Lemos
João Borges-Costa
Paulo Filipe
author_facet Diogo de Sousa
Yuliya Volovetska
Daniel Nunes
Carlos Lemos
João Borges-Costa
Paulo Filipe
author_sort Diogo de Sousa
collection DOAJ
description The resurgence of Mpox, predominantly among men who have sex with men (MSM), has prompted an analysis of its clinical manifestations and epidemiological patterns, particularly in individuals living with human immunodeficiency virus (HIV). This retrospective study aims to delineate and compare the clinical presentations and epidemiological characteristics of Mpox among HIV-positive and HIV-negative individuals. A total of 58 confirmed Mpox cases from a dermatology department in Lisbon were analyzed, focusing on mucocutaneous manifestations, systemic symptoms, and laboratory parameters. Our findings indicate no significant difference in disease severity and presentation between HIV-positive and HIV-negative groups, suggesting that HIV status may not be a determinant of Mpox severity, but rather an indicator of increased sexual risk behaviors, a recognized risk factor for Mpox transmission.
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spelling doaj.art-9a1b4f3de9d74c8a9a0fa9bd317f2f572024-02-23T15:37:32ZengMDPI AGViruses1999-49152024-01-0116222510.3390/v16020225Clinical and Epidemiological Characteristics of Mpox in HIV-Infected and Uninfected Men Who Have Sex with Men: A Retrospective Study in LisbonDiogo de Sousa0Yuliya Volovetska1Daniel Nunes2Carlos Lemos3João Borges-Costa4Paulo Filipe5Dermatology Department, Centro Hospitalar Universitário Lisboa Norte, 1349-008 Lisbon, PortugalClinical Pathology Department, Centro Hospitalar Universitário Lisboa Norte, 1349-008 Lisbon, PortugalClinical Pathology Department, Centro Hospitalar Universitário Lisboa Norte, 1349-008 Lisbon, PortugalClinical Pathology Department, Centro Hospitalar Universitário Lisboa Norte, 1349-008 Lisbon, PortugalDermatology Department, Centro Hospitalar Universitário Lisboa Norte, 1349-008 Lisbon, PortugalDermatology Department, Centro Hospitalar Universitário Lisboa Norte, 1349-008 Lisbon, PortugalThe resurgence of Mpox, predominantly among men who have sex with men (MSM), has prompted an analysis of its clinical manifestations and epidemiological patterns, particularly in individuals living with human immunodeficiency virus (HIV). This retrospective study aims to delineate and compare the clinical presentations and epidemiological characteristics of Mpox among HIV-positive and HIV-negative individuals. A total of 58 confirmed Mpox cases from a dermatology department in Lisbon were analyzed, focusing on mucocutaneous manifestations, systemic symptoms, and laboratory parameters. Our findings indicate no significant difference in disease severity and presentation between HIV-positive and HIV-negative groups, suggesting that HIV status may not be a determinant of Mpox severity, but rather an indicator of increased sexual risk behaviors, a recognized risk factor for Mpox transmission.https://www.mdpi.com/1999-4915/16/2/225MpoxHIVMSMepidemiology
spellingShingle Diogo de Sousa
Yuliya Volovetska
Daniel Nunes
Carlos Lemos
João Borges-Costa
Paulo Filipe
Clinical and Epidemiological Characteristics of Mpox in HIV-Infected and Uninfected Men Who Have Sex with Men: A Retrospective Study in Lisbon
Viruses
Mpox
HIV
MSM
epidemiology
title Clinical and Epidemiological Characteristics of Mpox in HIV-Infected and Uninfected Men Who Have Sex with Men: A Retrospective Study in Lisbon
title_full Clinical and Epidemiological Characteristics of Mpox in HIV-Infected and Uninfected Men Who Have Sex with Men: A Retrospective Study in Lisbon
title_fullStr Clinical and Epidemiological Characteristics of Mpox in HIV-Infected and Uninfected Men Who Have Sex with Men: A Retrospective Study in Lisbon
title_full_unstemmed Clinical and Epidemiological Characteristics of Mpox in HIV-Infected and Uninfected Men Who Have Sex with Men: A Retrospective Study in Lisbon
title_short Clinical and Epidemiological Characteristics of Mpox in HIV-Infected and Uninfected Men Who Have Sex with Men: A Retrospective Study in Lisbon
title_sort clinical and epidemiological characteristics of mpox in hiv infected and uninfected men who have sex with men a retrospective study in lisbon
topic Mpox
HIV
MSM
epidemiology
url https://www.mdpi.com/1999-4915/16/2/225
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