Clinical and Epidemiological Characteristics of Mpox in HIV-Infected and Uninfected Men Who Have Sex with Men: A Retrospective Study in Lisbon
The resurgence of Mpox, predominantly among men who have sex with men (MSM), has prompted an analysis of its clinical manifestations and epidemiological patterns, particularly in individuals living with human immunodeficiency virus (HIV). This retrospective study aims to delineate and compare the cl...
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MDPI AG
2024-01-01
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Online Access: | https://www.mdpi.com/1999-4915/16/2/225 |
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author | Diogo de Sousa Yuliya Volovetska Daniel Nunes Carlos Lemos João Borges-Costa Paulo Filipe |
author_facet | Diogo de Sousa Yuliya Volovetska Daniel Nunes Carlos Lemos João Borges-Costa Paulo Filipe |
author_sort | Diogo de Sousa |
collection | DOAJ |
description | The resurgence of Mpox, predominantly among men who have sex with men (MSM), has prompted an analysis of its clinical manifestations and epidemiological patterns, particularly in individuals living with human immunodeficiency virus (HIV). This retrospective study aims to delineate and compare the clinical presentations and epidemiological characteristics of Mpox among HIV-positive and HIV-negative individuals. A total of 58 confirmed Mpox cases from a dermatology department in Lisbon were analyzed, focusing on mucocutaneous manifestations, systemic symptoms, and laboratory parameters. Our findings indicate no significant difference in disease severity and presentation between HIV-positive and HIV-negative groups, suggesting that HIV status may not be a determinant of Mpox severity, but rather an indicator of increased sexual risk behaviors, a recognized risk factor for Mpox transmission. |
first_indexed | 2024-03-07T22:11:15Z |
format | Article |
id | doaj.art-9a1b4f3de9d74c8a9a0fa9bd317f2f57 |
institution | Directory Open Access Journal |
issn | 1999-4915 |
language | English |
last_indexed | 2024-03-07T22:11:15Z |
publishDate | 2024-01-01 |
publisher | MDPI AG |
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series | Viruses |
spelling | doaj.art-9a1b4f3de9d74c8a9a0fa9bd317f2f572024-02-23T15:37:32ZengMDPI AGViruses1999-49152024-01-0116222510.3390/v16020225Clinical and Epidemiological Characteristics of Mpox in HIV-Infected and Uninfected Men Who Have Sex with Men: A Retrospective Study in LisbonDiogo de Sousa0Yuliya Volovetska1Daniel Nunes2Carlos Lemos3João Borges-Costa4Paulo Filipe5Dermatology Department, Centro Hospitalar Universitário Lisboa Norte, 1349-008 Lisbon, PortugalClinical Pathology Department, Centro Hospitalar Universitário Lisboa Norte, 1349-008 Lisbon, PortugalClinical Pathology Department, Centro Hospitalar Universitário Lisboa Norte, 1349-008 Lisbon, PortugalClinical Pathology Department, Centro Hospitalar Universitário Lisboa Norte, 1349-008 Lisbon, PortugalDermatology Department, Centro Hospitalar Universitário Lisboa Norte, 1349-008 Lisbon, PortugalDermatology Department, Centro Hospitalar Universitário Lisboa Norte, 1349-008 Lisbon, PortugalThe resurgence of Mpox, predominantly among men who have sex with men (MSM), has prompted an analysis of its clinical manifestations and epidemiological patterns, particularly in individuals living with human immunodeficiency virus (HIV). This retrospective study aims to delineate and compare the clinical presentations and epidemiological characteristics of Mpox among HIV-positive and HIV-negative individuals. A total of 58 confirmed Mpox cases from a dermatology department in Lisbon were analyzed, focusing on mucocutaneous manifestations, systemic symptoms, and laboratory parameters. Our findings indicate no significant difference in disease severity and presentation between HIV-positive and HIV-negative groups, suggesting that HIV status may not be a determinant of Mpox severity, but rather an indicator of increased sexual risk behaviors, a recognized risk factor for Mpox transmission.https://www.mdpi.com/1999-4915/16/2/225MpoxHIVMSMepidemiology |
spellingShingle | Diogo de Sousa Yuliya Volovetska Daniel Nunes Carlos Lemos João Borges-Costa Paulo Filipe Clinical and Epidemiological Characteristics of Mpox in HIV-Infected and Uninfected Men Who Have Sex with Men: A Retrospective Study in Lisbon Viruses Mpox HIV MSM epidemiology |
title | Clinical and Epidemiological Characteristics of Mpox in HIV-Infected and Uninfected Men Who Have Sex with Men: A Retrospective Study in Lisbon |
title_full | Clinical and Epidemiological Characteristics of Mpox in HIV-Infected and Uninfected Men Who Have Sex with Men: A Retrospective Study in Lisbon |
title_fullStr | Clinical and Epidemiological Characteristics of Mpox in HIV-Infected and Uninfected Men Who Have Sex with Men: A Retrospective Study in Lisbon |
title_full_unstemmed | Clinical and Epidemiological Characteristics of Mpox in HIV-Infected and Uninfected Men Who Have Sex with Men: A Retrospective Study in Lisbon |
title_short | Clinical and Epidemiological Characteristics of Mpox in HIV-Infected and Uninfected Men Who Have Sex with Men: A Retrospective Study in Lisbon |
title_sort | clinical and epidemiological characteristics of mpox in hiv infected and uninfected men who have sex with men a retrospective study in lisbon |
topic | Mpox HIV MSM epidemiology |
url | https://www.mdpi.com/1999-4915/16/2/225 |
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