Ethyl 5-(4-chlorophenyl)-2-[(Z)-(methoxycarbonyl)methylene]-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate
The title compound, C19H17ClN2O5S, was synthesized by the reaction of ethyl 6-(4-chlorophenyl)-2-mercapto-4-methyl-1,6-dihydropyrimidine-5-carboxylate and dimethyl acetylenedicarboxylate in methanol. In the molecule, the nearly planar thiazole ring, with a mean deviation from the plane of 0.0108&...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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International Union of Crystallography
2009-02-01
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| Series: | Acta Crystallographica Section E |
| Online Access: | http://scripts.iucr.org/cgi-bin/paper?S1600536809002451 |
| _version_ | 1819294037415297024 |
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| author | Xiao-Fang Li Bin-Hong He Ning-Bo Zhou Zhao-Hui Hou |
| author_facet | Xiao-Fang Li Bin-Hong He Ning-Bo Zhou Zhao-Hui Hou |
| author_sort | Xiao-Fang Li |
| collection | DOAJ |
| description | The title compound, C19H17ClN2O5S, was synthesized by the reaction of ethyl 6-(4-chlorophenyl)-2-mercapto-4-methyl-1,6-dihydropyrimidine-5-carboxylate and dimethyl acetylenedicarboxylate in methanol. In the molecule, the nearly planar thiazole ring, with a mean deviation from the plane of 0.0108 (3) Å, is fused with a dihydropyrimidine ring in a flattened half-chair conformation. |
| first_indexed | 2024-12-24T04:19:57Z |
| format | Article |
| id | doaj.art-9a1bb0e79e0444818ad9b24018583419 |
| institution | Directory Open Access Journal |
| issn | 1600-5368 |
| language | English |
| last_indexed | 2024-12-24T04:19:57Z |
| publishDate | 2009-02-01 |
| publisher | International Union of Crystallography |
| record_format | Article |
| series | Acta Crystallographica Section E |
| spelling | doaj.art-9a1bb0e79e0444818ad9b240185834192022-12-21T17:15:50ZengInternational Union of CrystallographyActa Crystallographica Section E1600-53682009-02-01652o375o37510.1107/S1600536809002451Ethyl 5-(4-chlorophenyl)-2-[(Z)-(methoxycarbonyl)methylene]-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylateXiao-Fang LiBin-Hong HeNing-Bo ZhouZhao-Hui HouThe title compound, C19H17ClN2O5S, was synthesized by the reaction of ethyl 6-(4-chlorophenyl)-2-mercapto-4-methyl-1,6-dihydropyrimidine-5-carboxylate and dimethyl acetylenedicarboxylate in methanol. In the molecule, the nearly planar thiazole ring, with a mean deviation from the plane of 0.0108 (3) Å, is fused with a dihydropyrimidine ring in a flattened half-chair conformation.http://scripts.iucr.org/cgi-bin/paper?S1600536809002451 |
| spellingShingle | Xiao-Fang Li Bin-Hong He Ning-Bo Zhou Zhao-Hui Hou Ethyl 5-(4-chlorophenyl)-2-[(Z)-(methoxycarbonyl)methylene]-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate Acta Crystallographica Section E |
| title | Ethyl 5-(4-chlorophenyl)-2-[(Z)-(methoxycarbonyl)methylene]-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate |
| title_full | Ethyl 5-(4-chlorophenyl)-2-[(Z)-(methoxycarbonyl)methylene]-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate |
| title_fullStr | Ethyl 5-(4-chlorophenyl)-2-[(Z)-(methoxycarbonyl)methylene]-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate |
| title_full_unstemmed | Ethyl 5-(4-chlorophenyl)-2-[(Z)-(methoxycarbonyl)methylene]-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate |
| title_short | Ethyl 5-(4-chlorophenyl)-2-[(Z)-(methoxycarbonyl)methylene]-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate |
| title_sort | ethyl 5 4 chlorophenyl 2 z methoxycarbonyl methylene 7 methyl 3 oxo 3 5 dihydro 2h thiazolo 3 2 a pyrimidine 6 carboxylate |
| url | http://scripts.iucr.org/cgi-bin/paper?S1600536809002451 |
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