Cucurbitacins as Potent Chemo-Preventive Agents: Mechanistic Insight and Recent Trends

Cucurbitacins as Potent Chemo-Preventive Agents: Mechanistic Insight and Recent Trends

Cucurbitacins constitute a group of cucumber-derived dietary lipids, highly oxidized tetracyclic triterpenoids, with potential medical uses. These compounds are known to interact with a variety of recognized cellular targets to impede the growth of cancer cells. Accumulating evidence has suggested t...

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Bibliographic Details
Main Authors: Hardeep Singh Tuli, Prangya Rath, Abhishek Chauhan, Anuj Ranjan, Seema Ramniwas, Katrin Sak, Diwakar Aggarwal, Manoj Kumar, Kuldeep Dhama, E Hui Clarissa Lee, Kenneth Chun-Yong Yap, Sharah Mae Capinpin, Alan Prem Kumar
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Biomolecules
Subjects:
cucurbitacins
anti-proliferation
apoptotic
anti-angiogenic
anti-metastatic
synergism
Online Access:https://www.mdpi.com/2218-273X/13/1/57

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