Hippocampus-centred grey matter covariance networks predict the development and reversion of mild cognitive impairment

Hippocampus-centred grey matter covariance networks predict the development and reversion of mild cognitive impairment

Abstract Background Mild cognitive impairment (MCI) has been thought of as the transitional stage between normal ageing and Alzheimer’s disease, involving substantial changes in brain grey matter structures. As most previous studies have focused on single regions (e.g. the hippocampus) and their cha...

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Bibliographic Details
Main Authors: Mingxi Dang, Caishui Yang, Kewei Chen, Peng Lu, He Li, Zhanjun Zhang, for the Beijing Aging Brain Rejuvenation Initiative, for the Alzheimer’s Disease Neuroimaging Initiative
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Alzheimer’s Research & Therapy
Subjects:
Mild cognitive impairment
Covariance network
Hippocampus
Partial least square analyses
Random forest
Default network
Online Access:https://doi.org/10.1186/s13195-023-01167-z

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