The STF2p hydrophilin from Saccharomyces cerevisiae is required for dehydration stress tolerance.
The yeast Saccharomyces cerevisiae is able to overcome cell dehydration; cell metabolic activity is arrested during this period but restarts after rehydration. The yeast genes encoding hydrophilin proteins were characterised to determine their roles in the dehydration-resistant phenotype, and STF2p...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2012-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC3306391?pdf=render |
| _version_ | 1819160611613835264 |
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| author | Gema López-Martínez Boris Rodríguez-Porrata Mar Margalef-Català Ricardo Cordero-Otero |
| author_facet | Gema López-Martínez Boris Rodríguez-Porrata Mar Margalef-Català Ricardo Cordero-Otero |
| author_sort | Gema López-Martínez |
| collection | DOAJ |
| description | The yeast Saccharomyces cerevisiae is able to overcome cell dehydration; cell metabolic activity is arrested during this period but restarts after rehydration. The yeast genes encoding hydrophilin proteins were characterised to determine their roles in the dehydration-resistant phenotype, and STF2p was found to be a hydrophilin that is essential for survival after the desiccation-rehydration process. Deletion of STF2 promotes the production of reactive oxygen species and apoptotic cell death during stress conditions, whereas the overexpression of STF2, whose gene product localises to the cytoplasm, results in a reduction in ROS production upon oxidative stress as the result of the antioxidant capacity of the STF2p protein. |
| first_indexed | 2024-12-22T16:59:12Z |
| format | Article |
| id | doaj.art-9a212ec6a1f94310b95b086c1bdce898 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-22T16:59:12Z |
| publishDate | 2012-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-9a212ec6a1f94310b95b086c1bdce8982022-12-21T18:19:23ZengPublic Library of Science (PLoS)PLoS ONE1932-62032012-01-0173e3332410.1371/journal.pone.0033324The STF2p hydrophilin from Saccharomyces cerevisiae is required for dehydration stress tolerance.Gema López-MartínezBoris Rodríguez-PorrataMar Margalef-CatalàRicardo Cordero-OteroThe yeast Saccharomyces cerevisiae is able to overcome cell dehydration; cell metabolic activity is arrested during this period but restarts after rehydration. The yeast genes encoding hydrophilin proteins were characterised to determine their roles in the dehydration-resistant phenotype, and STF2p was found to be a hydrophilin that is essential for survival after the desiccation-rehydration process. Deletion of STF2 promotes the production of reactive oxygen species and apoptotic cell death during stress conditions, whereas the overexpression of STF2, whose gene product localises to the cytoplasm, results in a reduction in ROS production upon oxidative stress as the result of the antioxidant capacity of the STF2p protein.http://europepmc.org/articles/PMC3306391?pdf=render |
| spellingShingle | Gema López-Martínez Boris Rodríguez-Porrata Mar Margalef-Català Ricardo Cordero-Otero The STF2p hydrophilin from Saccharomyces cerevisiae is required for dehydration stress tolerance. PLoS ONE |
| title | The STF2p hydrophilin from Saccharomyces cerevisiae is required for dehydration stress tolerance. |
| title_full | The STF2p hydrophilin from Saccharomyces cerevisiae is required for dehydration stress tolerance. |
| title_fullStr | The STF2p hydrophilin from Saccharomyces cerevisiae is required for dehydration stress tolerance. |
| title_full_unstemmed | The STF2p hydrophilin from Saccharomyces cerevisiae is required for dehydration stress tolerance. |
| title_short | The STF2p hydrophilin from Saccharomyces cerevisiae is required for dehydration stress tolerance. |
| title_sort | stf2p hydrophilin from saccharomyces cerevisiae is required for dehydration stress tolerance |
| url | http://europepmc.org/articles/PMC3306391?pdf=render |
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