Proopiomelanocortin (POMC) and psychodermatology
Abstract Psychodermatology is the crossover discipline between Dermatology and Clinical Psychology and/or Psychiatry. It encompasses both Psychiatric diseases that present with cutaneous manifestations (such as delusional infestation) or more commonly, the psychiatric or psychological problems assoc...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-06-01
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| Series: | Skin Health and Disease |
| Online Access: | https://doi.org/10.1002/ski2.201 |
| _version_ | 1797814357675999232 |
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| author | George W. M. Millington Hannah E. Palmer |
| author_facet | George W. M. Millington Hannah E. Palmer |
| author_sort | George W. M. Millington |
| collection | DOAJ |
| description | Abstract Psychodermatology is the crossover discipline between Dermatology and Clinical Psychology and/or Psychiatry. It encompasses both Psychiatric diseases that present with cutaneous manifestations (such as delusional infestation) or more commonly, the psychiatric or psychological problems associated with skin disease, such as depression associated with psoriasis. These problems may be the result either of imbalance in or be the consequence of alteration in the homoeostatic endocrine mechanisms found in the systemic hypothalamic‐pituitary‐adrenal axis or in the local cutaneous corticotrophin‐releasing factor‐proopiomelanocortin‐corticosteroid axis. Alteration in either of these systems can lead to immune disruption and worsening of immune dermatoses and vice‐versa. These include diseases such as psoriasis, atopic eczema, acne, alopecia areata, vitiligo and melasma, all of which are known to be linked to stress. Similarly, stress and illnesses such as depression are linked with many immunodermatoses and may reflect alterations in the body's central and peripheral neuroendocrine stress pathways. It is important to consider issues pertaining to skin of colour, particularly with pigmentary disorders. |
| first_indexed | 2024-03-13T08:06:31Z |
| format | Article |
| id | doaj.art-9a243077c66348fc95411e76b1507fcc |
| institution | Directory Open Access Journal |
| issn | 2690-442X |
| language | English |
| last_indexed | 2024-03-13T08:06:31Z |
| publishDate | 2023-06-01 |
| publisher | Wiley |
| record_format | Article |
| series | Skin Health and Disease |
| spelling | doaj.art-9a243077c66348fc95411e76b1507fcc2023-06-01T05:13:40ZengWileySkin Health and Disease2690-442X2023-06-0133n/an/a10.1002/ski2.201Proopiomelanocortin (POMC) and psychodermatologyGeorge W. M. Millington0Hannah E. Palmer1Dermatology Department Norfolk and Norwich University Hospital Norwich UKNorwich Medical School Norwich UKAbstract Psychodermatology is the crossover discipline between Dermatology and Clinical Psychology and/or Psychiatry. It encompasses both Psychiatric diseases that present with cutaneous manifestations (such as delusional infestation) or more commonly, the psychiatric or psychological problems associated with skin disease, such as depression associated with psoriasis. These problems may be the result either of imbalance in or be the consequence of alteration in the homoeostatic endocrine mechanisms found in the systemic hypothalamic‐pituitary‐adrenal axis or in the local cutaneous corticotrophin‐releasing factor‐proopiomelanocortin‐corticosteroid axis. Alteration in either of these systems can lead to immune disruption and worsening of immune dermatoses and vice‐versa. These include diseases such as psoriasis, atopic eczema, acne, alopecia areata, vitiligo and melasma, all of which are known to be linked to stress. Similarly, stress and illnesses such as depression are linked with many immunodermatoses and may reflect alterations in the body's central and peripheral neuroendocrine stress pathways. It is important to consider issues pertaining to skin of colour, particularly with pigmentary disorders.https://doi.org/10.1002/ski2.201 |
| spellingShingle | George W. M. Millington Hannah E. Palmer Proopiomelanocortin (POMC) and psychodermatology Skin Health and Disease |
| title | Proopiomelanocortin (POMC) and psychodermatology |
| title_full | Proopiomelanocortin (POMC) and psychodermatology |
| title_fullStr | Proopiomelanocortin (POMC) and psychodermatology |
| title_full_unstemmed | Proopiomelanocortin (POMC) and psychodermatology |
| title_short | Proopiomelanocortin (POMC) and psychodermatology |
| title_sort | proopiomelanocortin pomc and psychodermatology |
| url | https://doi.org/10.1002/ski2.201 |
| work_keys_str_mv | AT georgewmmillington proopiomelanocortinpomcandpsychodermatology AT hannahepalmer proopiomelanocortinpomcandpsychodermatology |