Contribution of Oxidative Stress to Endothelial Dysfunction in Hypertension

Contribution of Oxidative Stress to Endothelial Dysfunction in Hypertension

Endothelial dysfunction is the hallmark of hypertension, which is a multifactorial disorder. In the cardiovascular system reactive oxygen species play a pivotal role in controlling the endothelial function and vascular tone. Physiologically, the endothelium-derived relaxing factors (EDRFs) and endot...

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Bibliographic Details
Main Authors: Bruno Rodrigues Silva, Laena ePernomian, Lusiane Maria Bendhack
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-12-01
Series:Frontiers in Physiology
Subjects:
Hypertension
Oxidative Stress
endothelial dysfunction
vascular relaxation
vascular contraction
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Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00441/full

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