Clinical and Pathological Features of Double-Hit and Triple-Hit High-Grade B-Cell Lymphomas: A Retrospective Study from Three Portuguese Tertiary Centers

Clinical and Pathological Features of Double-Hit and Triple-Hit High-Grade B-Cell Lymphomas: A Retrospective Study from Three Portuguese Tertiary Centers

   Background: High-grade B-cell lymphoma (HGBL) with rearrangements of MYC and BCL2 and/or BCL6, called double and triple-hit lymphomas (DTH-HGBL), are lymphoid malignancies with inferior outcomes when treated with standard chemotherapy. The identification of DTH-HGBL cases is challenging, cons...

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Bibliographic Details
Main Authors: Rui Almeida, Carlos Abrantes, Davide Gigliano, Rui Caetano Oliveira, Paulo Teixeira, Marta Viegas, Ângelo Rodrigues, Maria José Julião
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2022-04-01
Series:International Journal of Hematology-Oncology and Stem Cell Research
Subjects:
High-grade; B-cell; Lymphoma; Cytogenetics; Immunohistochemistry; Double-hit; Triple-hit
Online Access:https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/1351

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