S116: LONG-TERM EFFICACY AND SAFETY OF THE ORAL PYRUVATE KINASE ACTIVATOR MITAPIVAT IN ADULTS WITH NON—TRANSFUSION-DEPENDENT ALPHA- OR BETA-THALASSEMIA - K Kuo; D Layton; A Lal; H Al-Samkari; J Bhatia; P Kosinski; B Tong; M Lynch; K Uhlig; E Vichinsky (HemaSphere, 2022)