Effect of sodium–glucose cotransporter-2 inhibitors on aldosterone-to-renin ratio in diabetic patients with hypertension: a retrospective observational study

Effect of sodium–glucose cotransporter-2 inhibitors on aldosterone-to-renin ratio in diabetic patients with hypertension: a retrospective observational study

Abstract Background Plasma aldosterone-to-renin ratio (ARR) is popularly used for screening primary aldosteronism (PA). Some medications, including diuretics, are known to have an effect on ARR and cause false-negative and false-positive results in PA screening. Currently, there are no studies on th...

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Main Authors: Toshitaka Sawamura, Shigehiro Karashima, Satoshi Nagase, Hidetaka Nambo, Eiko Shimizu, Takuya Higashitani, Daisuke Aono, Azusa Ohbatake, Mitsuhiro Kometani, Masashi Demura, Kenji Furukawa, Yoshiyu Takeda, Takashi Yoneda
Format: Article
Language:English
Published: BMC 2020-11-01
Series:BMC Endocrine Disorders
Subjects:
SGLT2 inhibitor
Aldosterone-to-renin ratio
Renin-angiotensin-aldosterone system
Primary aldosteronism
Diabetes
Hypertension
Online Access:https://doi.org/10.1186/s12902-020-00656-8

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