Cytotoxic and Transcriptomic Effects in Avian Hepatocytes Exposed to a Complex Mixture from Air Samples, and Their Relation to the Organic Flame Retardant Signature

Cytotoxic and Transcriptomic Effects in Avian Hepatocytes Exposed to a Complex Mixture from Air Samples, and Their Relation to the Organic Flame Retardant Signature

Assessing complex environmental mixtures and their effects is challenging. In this study, we evaluate the utility of an avian in vitro screening approach to determine the effects of passive air sampler extracts collected from different global megacities on cytotoxicity and gene expression. Concentra...

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Bibliographic Details
Main Authors: Kelsey Ha, Pu Xia, Doug Crump, Amandeep Saini, Tom Harner, Jason O’Brien
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Toxics
Subjects:
organic flame retardants (OFRs)
complex mixtures
in vitro screening
PCR array
passive air sampling
chicken embryonic hepatocytes (CEH)
Online Access:https://www.mdpi.com/2305-6304/9/12/324

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