Recurrent Myxoid Chondrosarcoma of Mandible: A Case Report
Myxoid chondrosarcoma is a rare malignant neoplasm of bone or soft tissue origin, characterised by the presence of chondroid and myxoid matrix. These are traditionally radio resistant tumours, so wide surgical resection remains the mainstay of treatment. However, radiotherapy is generally advised...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2021-04-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://www.jcdr.net/articles/PDF/14754/44659_CE[Ra1]_F[SK]_PF1(SC_RK)_PN(KM).pdf |
| _version_ | 1818662155514281984 |
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| author | Prabha Verma Rohini Khurana Sambit Swarup Nanda Satyajeet Rath |
| author_facet | Prabha Verma Rohini Khurana Sambit Swarup Nanda Satyajeet Rath |
| author_sort | Prabha Verma |
| collection | DOAJ |
| description | Myxoid chondrosarcoma is a rare malignant neoplasm of bone or soft tissue origin, characterised by the presence of chondroid and myxoid
matrix. These are traditionally radio resistant tumours, so wide surgical resection remains the mainstay of treatment. However, radiotherapy
is generally advised for high-grade lesions with poor prognostic factors with adjuvant chemotherapy. The treatment decisions are primarily
guided by the histological grade, extent of surgical resection, and site of the neoplasm. A case of a 28-year-old male who presented with
recurrent painful swelling in the mandibular region is discussed here. To date, very few cases of Extraskeletal Myxoid Chondrosarcoma (EMC)
occurring in the mandible region have been reported. So, due to the paucity of available literature, controversies still exist regarding effective
treatment approaches in newly diagnosed and recurrent cases. This case reports the clinical presentation, histopathology, radiological
characteristics, immune profile, and treatment modalities used in EMC with a comprehensive and relevant review of the literature. |
| first_indexed | 2024-12-17T04:56:27Z |
| format | Article |
| id | doaj.art-9a37fe40aff04ced80bae8e388c02e91 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-17T04:56:27Z |
| publishDate | 2021-04-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-9a37fe40aff04ced80bae8e388c02e912022-12-21T22:02:41ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2021-04-01154XD01XD0210.7860/JCDR/2021/44659.14754Recurrent Myxoid Chondrosarcoma of Mandible: A Case ReportPrabha Verma0Rohini Khurana1Sambit Swarup Nanda2Satyajeet Rath3Senior Resident, Department of Radiation Oncology, Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.Professor, Department of Radiation Oncology, Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.Assistant Professor, Department of Radiation Oncology, Homi Bhabha Cancer Hospital, Varansi, Uttar Pradesh, India.Senior Resident, Department of Radiation Oncology, Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.Myxoid chondrosarcoma is a rare malignant neoplasm of bone or soft tissue origin, characterised by the presence of chondroid and myxoid matrix. These are traditionally radio resistant tumours, so wide surgical resection remains the mainstay of treatment. However, radiotherapy is generally advised for high-grade lesions with poor prognostic factors with adjuvant chemotherapy. The treatment decisions are primarily guided by the histological grade, extent of surgical resection, and site of the neoplasm. A case of a 28-year-old male who presented with recurrent painful swelling in the mandibular region is discussed here. To date, very few cases of Extraskeletal Myxoid Chondrosarcoma (EMC) occurring in the mandible region have been reported. So, due to the paucity of available literature, controversies still exist regarding effective treatment approaches in newly diagnosed and recurrent cases. This case reports the clinical presentation, histopathology, radiological characteristics, immune profile, and treatment modalities used in EMC with a comprehensive and relevant review of the literature.https://www.jcdr.net/articles/PDF/14754/44659_CE[Ra1]_F[SK]_PF1(SC_RK)_PN(KM).pdfbone neoplasmground-glassmetastasisradiationsun-burst |
| spellingShingle | Prabha Verma Rohini Khurana Sambit Swarup Nanda Satyajeet Rath Recurrent Myxoid Chondrosarcoma of Mandible: A Case Report Journal of Clinical and Diagnostic Research bone neoplasm ground-glass metastasis radiation sun-burst |
| title | Recurrent Myxoid Chondrosarcoma of Mandible: A Case Report |
| title_full | Recurrent Myxoid Chondrosarcoma of Mandible: A Case Report |
| title_fullStr | Recurrent Myxoid Chondrosarcoma of Mandible: A Case Report |
| title_full_unstemmed | Recurrent Myxoid Chondrosarcoma of Mandible: A Case Report |
| title_short | Recurrent Myxoid Chondrosarcoma of Mandible: A Case Report |
| title_sort | recurrent myxoid chondrosarcoma of mandible a case report |
| topic | bone neoplasm ground-glass metastasis radiation sun-burst |
| url | https://www.jcdr.net/articles/PDF/14754/44659_CE[Ra1]_F[SK]_PF1(SC_RK)_PN(KM).pdf |
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