Delineating the role of single-nucleotide polymorphism of CYP19 gene on aromatase activity in South Indian women with polycystic ovary syndrome

Abstract Background Polycystic ovary syndrome is a common multifactorial endocrinopathy disorder affecting 5–15% of reproductive women worldwide. The CYP19 gene encodes key enzyme aromatase involved in androgen-to-estrogen conversion which plays a crucial role in the pathophysiology of the syndrome....

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Bibliographic Details
Main Authors: Pravesh Hegde, Shilpa S. Shetty, Prasanna Kumar Shetty, Lakshmi Manjeera, D. Prashanth Shetty, Suchetha Kumari
Format: Article
Language:English
Published: SpringerOpen 2023-08-01
Series:Journal of Genetic Engineering and Biotechnology
Subjects:
Online Access:https://doi.org/10.1186/s43141-023-00540-7