Perinatal asphyxia reduces dentate granule cells and exacerbates methamphetamine-induced hyperlocomotion in adulthood.
BACKGROUND: Obstetric complications have been regarded as a risk factor for schizophrenia later in life. One of the mechanisms underlying the association is postulated to be a hypoxic process in the brain in the offspring around the time of birth. Hippocampus is one of the brain regions implicated i...
Main Authors: | Tomoyasu Wakuda, Hideo Matsuzaki, Katsuaki Suzuki, Yasuhide Iwata, Chie Shinmura, Shiro Suda, Keiko Iwata, Shigeyuki Yamamoto, Genichi Sugihara, Kenji J Tsuchiya, Takatoshi Ueki, Kazuhiko Nakamura, Daiichiro Nakahara, Nori Takei, Norio Mori |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2572851?pdf=render |
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