Within-host evolution of Helicobacter pylori shaped by niche-specific adaptation, intragastric migrations and selective sweeps

Within-host evolution of Helicobacter pylori shaped by niche-specific adaptation, intragastric migrations and selective sweeps

Helicobacter pylori, a bacterial pathogen that infects human stomachs, has high genetic diversity across hosts. Here, Ailloud et al. reveal genetic structuring of H. pylori populations among different stomach regions of individual hosts and find signals of genetic associations with stomach region.

Bibliographic Details
Main Authors: Florent Ailloud, Xavier Didelot, Sabrina Woltemate, Gudrun Pfaffinger, Jörg Overmann, Ruth Christiane Bader, Christian Schulz, Peter Malfertheiner, Sebastian Suerbaum
Format: Article
Language:English
Published: Nature Portfolio 2019-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-10050-1

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