Potential Therapeutic Benefits of Honey in Neurological Disorders: The Role of Polyphenols

Honey is the principal premier product of beekeeping familiar to Homo for centuries. In every geological era and culture, evidence can be traced to the potential usefulness of honey in several ailments. With the advent of recent scientific approaches, honey has been proclaimed as a potent complement...

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Main Authors: Arslan Iftikhar, Rimsha Nausheen, Humaira Muzaffar, Muhammad Ahsan Naeem, Muhammad Farooq, Mohsin Khurshid, Ahmad Almatroudi, Faris Alrumaihi, Khaled S. Allemailem, Haseeb Anwar
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/27/10/3297
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author Arslan Iftikhar
Rimsha Nausheen
Humaira Muzaffar
Muhammad Ahsan Naeem
Muhammad Farooq
Mohsin Khurshid
Ahmad Almatroudi
Faris Alrumaihi
Khaled S. Allemailem
Haseeb Anwar
author_facet Arslan Iftikhar
Rimsha Nausheen
Humaira Muzaffar
Muhammad Ahsan Naeem
Muhammad Farooq
Mohsin Khurshid
Ahmad Almatroudi
Faris Alrumaihi
Khaled S. Allemailem
Haseeb Anwar
author_sort Arslan Iftikhar
collection DOAJ
description Honey is the principal premier product of beekeeping familiar to Homo for centuries. In every geological era and culture, evidence can be traced to the potential usefulness of honey in several ailments. With the advent of recent scientific approaches, honey has been proclaimed as a potent complementary and alternative medicine for the management and treatment of several maladies including various neurological disorders such as Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, and multiple sclerosis, etc. In the literature archive, oxidative stress and the deprivation of antioxidants are believed to be the paramount cause of many of these neuropathies. Since different types of honey are abundant with certain antioxidants, primarily in the form of diverse polyphenols, honey is undoubtedly a strong pharmaceutic candidate against multiple neurological diseases. In this review, we have indexed and comprehended the involved mechanisms of various constituent polyphenols including different phenolic acids, flavonoids, and other phytochemicals that manifest multiple antioxidant effects in various neurological disorders. All these mechanistic interpretations of the nutritious components of honey explain and justify the potential recommendation of sweet nectar in ameliorating the burden of neurological disorders that have significantly increased across the world in the last few decades.
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spelling doaj.art-9a3e6a766e644771b1d52b7448897c9d2023-11-23T12:24:13ZengMDPI AGMolecules1420-30492022-05-012710329710.3390/molecules27103297Potential Therapeutic Benefits of Honey in Neurological Disorders: The Role of PolyphenolsArslan Iftikhar0Rimsha Nausheen1Humaira Muzaffar2Muhammad Ahsan Naeem3Muhammad Farooq4Mohsin Khurshid5Ahmad Almatroudi6Faris Alrumaihi7Khaled S. Allemailem8Haseeb Anwar9Department of Physiology, Government College University Faisalabad, Faisalabad 38000, PakistanDepartment of Physiology, Government College University Faisalabad, Faisalabad 38000, PakistanDepartment of Physiology, Government College University Faisalabad, Faisalabad 38000, PakistanDepartment of Basic Sciences, KBCMA College of Veterinary and Animal Sciences, Narowal 51600, PakistanDepartment of Clinical Sciences, College of Veterinary and Animal Sciences, Jhang 35200, PakistanDepartment of Microbiology, Government College University Faisalabad, Faisalabad 38000, PakistanDepartment of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah 51452, Saudi ArabiaDepartment of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah 51452, Saudi ArabiaDepartment of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah 51452, Saudi ArabiaDepartment of Physiology, Government College University Faisalabad, Faisalabad 38000, PakistanHoney is the principal premier product of beekeeping familiar to Homo for centuries. In every geological era and culture, evidence can be traced to the potential usefulness of honey in several ailments. With the advent of recent scientific approaches, honey has been proclaimed as a potent complementary and alternative medicine for the management and treatment of several maladies including various neurological disorders such as Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, and multiple sclerosis, etc. In the literature archive, oxidative stress and the deprivation of antioxidants are believed to be the paramount cause of many of these neuropathies. Since different types of honey are abundant with certain antioxidants, primarily in the form of diverse polyphenols, honey is undoubtedly a strong pharmaceutic candidate against multiple neurological diseases. In this review, we have indexed and comprehended the involved mechanisms of various constituent polyphenols including different phenolic acids, flavonoids, and other phytochemicals that manifest multiple antioxidant effects in various neurological disorders. All these mechanistic interpretations of the nutritious components of honey explain and justify the potential recommendation of sweet nectar in ameliorating the burden of neurological disorders that have significantly increased across the world in the last few decades.https://www.mdpi.com/1420-3049/27/10/3297honeypolyphenolslongevityflavonoids
spellingShingle Arslan Iftikhar
Rimsha Nausheen
Humaira Muzaffar
Muhammad Ahsan Naeem
Muhammad Farooq
Mohsin Khurshid
Ahmad Almatroudi
Faris Alrumaihi
Khaled S. Allemailem
Haseeb Anwar
Potential Therapeutic Benefits of Honey in Neurological Disorders: The Role of Polyphenols
Molecules
honey
polyphenols
longevity
flavonoids
title Potential Therapeutic Benefits of Honey in Neurological Disorders: The Role of Polyphenols
title_full Potential Therapeutic Benefits of Honey in Neurological Disorders: The Role of Polyphenols
title_fullStr Potential Therapeutic Benefits of Honey in Neurological Disorders: The Role of Polyphenols
title_full_unstemmed Potential Therapeutic Benefits of Honey in Neurological Disorders: The Role of Polyphenols
title_short Potential Therapeutic Benefits of Honey in Neurological Disorders: The Role of Polyphenols
title_sort potential therapeutic benefits of honey in neurological disorders the role of polyphenols
topic honey
polyphenols
longevity
flavonoids
url https://www.mdpi.com/1420-3049/27/10/3297
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