Improving effect of oleic acid-mediated sodium caseinate-based encapsulation in an ultrasound field on the thermal stability and bioaccessibility of quercetin
The simultaneous improvement of quercetin (QUE) processing stability and bioavailability has always presented a technical challenge during food processing. This study constructed a water-soluble carrier consisting of oleic acid (OA) and sodium caseinate (NaCas) in an ultrasonic field and investigate...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022-11-01
|
| Series: | Ultrasonics Sonochemistry |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1350417722002656 |
| _version_ | 1811189280176865280 |
|---|---|
| author | Shengnan Wang Yunjun Liu Yixiang Liu Zixin Guo Jie Li |
| author_facet | Shengnan Wang Yunjun Liu Yixiang Liu Zixin Guo Jie Li |
| author_sort | Shengnan Wang |
| collection | DOAJ |
| description | The simultaneous improvement of quercetin (QUE) processing stability and bioavailability has always presented a technical challenge during food processing. This study constructed a water-soluble carrier consisting of oleic acid (OA) and sodium caseinate (NaCas) in an ultrasonic field and investigated the effect of its encapsulation on improving the thermal stability and bioaccessibility of QUE. The results showed that the OA and NaCas generated uniform, stable water-soluble particles with a poly dispersity index (PDI) below 0.3 and an absolute value of Zeta potential above 30 mV in optimized conditions (a protein concentration of 4 mg/mL, ultrasonic power of 300 W, and ultrasonic time of 5 min). OA-NaCas mass ratio of 1:40, 1:15, 1:8, and 1:4 was selected for QUE loading to compare its encapsulation effect at different mass ratios. Compared with the NaCas without OA, the QUE embedding rate reached 95 % at OA-NaCas mass ratios of 1:15 and 1:8. In addition, the transmission electron microscopy (TEM) images confirmed that QUE was embedded in OA-NaCas particles, forming regular, spherical OA-NaCas-QUE particles at mass ratios or 1:15 and 1:8. Next, when heated at 80 °C for 120 min, the OA-NaCas (OA:NaCas, 1:15, 1:8, and W/W) particles significantly improved the QUE retention rate. The simulated in vitro gastrointestinal digestion experiments showed that the QUE bioaccessibility increased from 25 % to more than 60 % when it was encapsulated in OA-NaCas (OA:NaCas, 1:15, 1:8, and W/W) particles. These results indicated that the OA-NaCas complex was suitable as a hydrophilic delivery carrier of fat-soluble polyphenols. |
| first_indexed | 2024-04-11T14:33:19Z |
| format | Article |
| id | doaj.art-9a3ffe67ae1547a7a75c5ef33281671a |
| institution | Directory Open Access Journal |
| issn | 1350-4177 |
| language | English |
| last_indexed | 2024-04-11T14:33:19Z |
| publishDate | 2022-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Ultrasonics Sonochemistry |
| spelling | doaj.art-9a3ffe67ae1547a7a75c5ef33281671a2022-12-22T04:18:28ZengElsevierUltrasonics Sonochemistry1350-41772022-11-0190106169Improving effect of oleic acid-mediated sodium caseinate-based encapsulation in an ultrasound field on the thermal stability and bioaccessibility of quercetinShengnan Wang0Yunjun Liu1Yixiang Liu2Zixin Guo3Jie Li4College of Ocean Food and Biological Engineering, Jimei University, Xiamen, Fujian 361021, ChinaCollege of Ocean Food and Biological Engineering, Jimei University, Xiamen, Fujian 361021, ChinaCollege of Ocean Food and Biological Engineering, Jimei University, Xiamen, Fujian 361021, China; Collaborative Innovation Center of Provincial and Ministerial Co-construction for Marine Food Deep Processing, Dalian Polytechnic University, Dalian 116034, China; Corresponding author.College of Ocean Food and Biological Engineering, Jimei University, Xiamen, Fujian 361021, ChinaCollege of Ocean Food and Biological Engineering, Jimei University, Xiamen, Fujian 361021, ChinaThe simultaneous improvement of quercetin (QUE) processing stability and bioavailability has always presented a technical challenge during food processing. This study constructed a water-soluble carrier consisting of oleic acid (OA) and sodium caseinate (NaCas) in an ultrasonic field and investigated the effect of its encapsulation on improving the thermal stability and bioaccessibility of QUE. The results showed that the OA and NaCas generated uniform, stable water-soluble particles with a poly dispersity index (PDI) below 0.3 and an absolute value of Zeta potential above 30 mV in optimized conditions (a protein concentration of 4 mg/mL, ultrasonic power of 300 W, and ultrasonic time of 5 min). OA-NaCas mass ratio of 1:40, 1:15, 1:8, and 1:4 was selected for QUE loading to compare its encapsulation effect at different mass ratios. Compared with the NaCas without OA, the QUE embedding rate reached 95 % at OA-NaCas mass ratios of 1:15 and 1:8. In addition, the transmission electron microscopy (TEM) images confirmed that QUE was embedded in OA-NaCas particles, forming regular, spherical OA-NaCas-QUE particles at mass ratios or 1:15 and 1:8. Next, when heated at 80 °C for 120 min, the OA-NaCas (OA:NaCas, 1:15, 1:8, and W/W) particles significantly improved the QUE retention rate. The simulated in vitro gastrointestinal digestion experiments showed that the QUE bioaccessibility increased from 25 % to more than 60 % when it was encapsulated in OA-NaCas (OA:NaCas, 1:15, 1:8, and W/W) particles. These results indicated that the OA-NaCas complex was suitable as a hydrophilic delivery carrier of fat-soluble polyphenols.http://www.sciencedirect.com/science/article/pii/S1350417722002656QuercetinOleic acidSodium caseinateUltrasoundSelf-assemblyBioaccessibility |
| spellingShingle | Shengnan Wang Yunjun Liu Yixiang Liu Zixin Guo Jie Li Improving effect of oleic acid-mediated sodium caseinate-based encapsulation in an ultrasound field on the thermal stability and bioaccessibility of quercetin Ultrasonics Sonochemistry Quercetin Oleic acid Sodium caseinate Ultrasound Self-assembly Bioaccessibility |
| title | Improving effect of oleic acid-mediated sodium caseinate-based encapsulation in an ultrasound field on the thermal stability and bioaccessibility of quercetin |
| title_full | Improving effect of oleic acid-mediated sodium caseinate-based encapsulation in an ultrasound field on the thermal stability and bioaccessibility of quercetin |
| title_fullStr | Improving effect of oleic acid-mediated sodium caseinate-based encapsulation in an ultrasound field on the thermal stability and bioaccessibility of quercetin |
| title_full_unstemmed | Improving effect of oleic acid-mediated sodium caseinate-based encapsulation in an ultrasound field on the thermal stability and bioaccessibility of quercetin |
| title_short | Improving effect of oleic acid-mediated sodium caseinate-based encapsulation in an ultrasound field on the thermal stability and bioaccessibility of quercetin |
| title_sort | improving effect of oleic acid mediated sodium caseinate based encapsulation in an ultrasound field on the thermal stability and bioaccessibility of quercetin |
| topic | Quercetin Oleic acid Sodium caseinate Ultrasound Self-assembly Bioaccessibility |
| url | http://www.sciencedirect.com/science/article/pii/S1350417722002656 |
| work_keys_str_mv | AT shengnanwang improvingeffectofoleicacidmediatedsodiumcaseinatebasedencapsulationinanultrasoundfieldonthethermalstabilityandbioaccessibilityofquercetin AT yunjunliu improvingeffectofoleicacidmediatedsodiumcaseinatebasedencapsulationinanultrasoundfieldonthethermalstabilityandbioaccessibilityofquercetin AT yixiangliu improvingeffectofoleicacidmediatedsodiumcaseinatebasedencapsulationinanultrasoundfieldonthethermalstabilityandbioaccessibilityofquercetin AT zixinguo improvingeffectofoleicacidmediatedsodiumcaseinatebasedencapsulationinanultrasoundfieldonthethermalstabilityandbioaccessibilityofquercetin AT jieli improvingeffectofoleicacidmediatedsodiumcaseinatebasedencapsulationinanultrasoundfieldonthethermalstabilityandbioaccessibilityofquercetin |