Inhibition of Tumor Growth, Angiogenesis, and Microcirculation by the Novel Flk-1 Inhibitor SU5416 as Assessed by Intravital Multi-fluorescence Videomicroscopy
Vascular endothelial growth factor (VEGF) plays a fundamental role in mediating tumor angiogenesis and tumor growth. Here we investigate the direct effect of a novel small molecule inhibitor of the Flk-1-mediated signal transduction pathway of VEGF, SU5416, on tumor angiogenesis and microhemodynamic...
| Glavni autori: | , , , , , , , |
|---|---|
| Format: | Članak |
| Jezik: | English |
| Izdano: |
Elsevier
1999-04-01
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| Serija: | Neoplasia: An International Journal for Oncology Research |
| Teme: | |
| Online pristup: | http://www.sciencedirect.com/science/article/pii/S1476558699800335 |