Pierre Robin Sequence and 3D Printed Personalized Composite Appliances in Interdisciplinary Approach

This paper introduces a complex novel concept and methodology for the creation of personalized biomedical appliances 3D-printed from certified biocompatible photopolymer resin Dental LT Clear (V2). The explained workflow includes intraoral and CT scanning, patient virtualization, digital appliance d...

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Main Authors: Andrej Thurzo, Barbora Šufliarsky, Wanda Urbanová, Martin Čverha, Martin Strunga, Ivan Varga
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Polymers
Subjects:
Online Access:https://www.mdpi.com/2073-4360/14/18/3858
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author Andrej Thurzo
Barbora Šufliarsky
Wanda Urbanová
Martin Čverha
Martin Strunga
Ivan Varga
author_facet Andrej Thurzo
Barbora Šufliarsky
Wanda Urbanová
Martin Čverha
Martin Strunga
Ivan Varga
author_sort Andrej Thurzo
collection DOAJ
description This paper introduces a complex novel concept and methodology for the creation of personalized biomedical appliances 3D-printed from certified biocompatible photopolymer resin Dental LT Clear (V2). The explained workflow includes intraoral and CT scanning, patient virtualization, digital appliance design, additive manufacturing, and clinical application with evaluation of the appliance intended for patients with cranio-facial syndromes. The presented concept defines virtual 3D fusion of intraoral optical scan and segmented CT as sufficient and accurate data defining the 3D surface of the face, intraoral and airway morphology necessary for the 3D design of complex personalized intraoral and extraoral parts of the orthopedic appliance. A central aspect of the concept is a feasible utilization of composite resin for biomedical prototyping of the sequence of marginally different appliances necessary to keep the pace with the patient rapid growth. Affordability, noninvasiveness, and practicality of the appliance update process shall be highlighted. The methodology is demonstrated on a particular case of two-year-old infant with Pierre Robin sequence. Materialization by additive manufacturing of this photopolymer provides a highly durable and resistant-to-fracture two-part appliance similar to a Tübingen palatal plate, for example. The paper concludes with the viability of the described method and material upon interdisciplinary clinical evaluation of experts from departments of orthodontics and cleft anomalies, pediatric pneumology and phthisiology, and pediatric otorhinolaryngology.
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spelling doaj.art-9a46daa368424417880921a08fbb39792023-11-23T18:31:16ZengMDPI AGPolymers2073-43602022-09-011418385810.3390/polym14183858Pierre Robin Sequence and 3D Printed Personalized Composite Appliances in Interdisciplinary ApproachAndrej Thurzo0Barbora Šufliarsky1Wanda Urbanová2Martin Čverha3Martin Strunga4Ivan Varga5Department of Stomatology and Maxillofacial Surgery, Faculty of Medicine, Comenius University in Bratislava, 81250 Bratislava, SlovakiaDepartment of Oral and Maxillofacial Surgery, Faculty of Medicine, Comenius University in Bratislava and University Hospital, 81372 Bratislava, SlovakiaDepartment of Orthodontics and Cleft Anomalies, Faculty Hospital Kralovske Vinohrady, Dental Clinic 3rd Medical Faculty Charles University, 10034 Prague, Czech RepublicClinic of Pediatric Otorhinolaryngology of the Medical Faculty Comenius University in Bratislava, 83340 Bratislava, SlovakiaDepartment of Stomatology and Maxillofacial Surgery, Faculty of Medicine, Comenius University in Bratislava, 81250 Bratislava, SlovakiaDepartment of Histology and Embryology, Faculty of Medicine, Comenius University in Bratislava, 81372 Bratislava, SlovakiaThis paper introduces a complex novel concept and methodology for the creation of personalized biomedical appliances 3D-printed from certified biocompatible photopolymer resin Dental LT Clear (V2). The explained workflow includes intraoral and CT scanning, patient virtualization, digital appliance design, additive manufacturing, and clinical application with evaluation of the appliance intended for patients with cranio-facial syndromes. The presented concept defines virtual 3D fusion of intraoral optical scan and segmented CT as sufficient and accurate data defining the 3D surface of the face, intraoral and airway morphology necessary for the 3D design of complex personalized intraoral and extraoral parts of the orthopedic appliance. A central aspect of the concept is a feasible utilization of composite resin for biomedical prototyping of the sequence of marginally different appliances necessary to keep the pace with the patient rapid growth. Affordability, noninvasiveness, and practicality of the appliance update process shall be highlighted. The methodology is demonstrated on a particular case of two-year-old infant with Pierre Robin sequence. Materialization by additive manufacturing of this photopolymer provides a highly durable and resistant-to-fracture two-part appliance similar to a Tübingen palatal plate, for example. The paper concludes with the viability of the described method and material upon interdisciplinary clinical evaluation of experts from departments of orthodontics and cleft anomalies, pediatric pneumology and phthisiology, and pediatric otorhinolaryngology.https://www.mdpi.com/2073-4360/14/18/3858biocompatible photopolymer resin3D printed orthopedic applianceorthodonticsTübingen palatal plateInfantscraniofacial anomalies
spellingShingle Andrej Thurzo
Barbora Šufliarsky
Wanda Urbanová
Martin Čverha
Martin Strunga
Ivan Varga
Pierre Robin Sequence and 3D Printed Personalized Composite Appliances in Interdisciplinary Approach
Polymers
biocompatible photopolymer resin
3D printed orthopedic appliance
orthodontics
Tübingen palatal plate
Infants
craniofacial anomalies
title Pierre Robin Sequence and 3D Printed Personalized Composite Appliances in Interdisciplinary Approach
title_full Pierre Robin Sequence and 3D Printed Personalized Composite Appliances in Interdisciplinary Approach
title_fullStr Pierre Robin Sequence and 3D Printed Personalized Composite Appliances in Interdisciplinary Approach
title_full_unstemmed Pierre Robin Sequence and 3D Printed Personalized Composite Appliances in Interdisciplinary Approach
title_short Pierre Robin Sequence and 3D Printed Personalized Composite Appliances in Interdisciplinary Approach
title_sort pierre robin sequence and 3d printed personalized composite appliances in interdisciplinary approach
topic biocompatible photopolymer resin
3D printed orthopedic appliance
orthodontics
Tübingen palatal plate
Infants
craniofacial anomalies
url https://www.mdpi.com/2073-4360/14/18/3858
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