Associations of Transcription Factor 21 Gene Polymorphisms with the Growth and Body Composition Traits in Broilers
This study aims to identify molecular marker loci that could be applied in broiler breeding programs. In this study, we used public databases to locate the <i>Transcription factor 21</i> (<i>TCF21</i>) gene that affected the economically important traits in broilers. Ten sing...
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MDPI AG
2022-02-01
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| Series: | Animals |
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| Online Access: | https://www.mdpi.com/2076-2615/12/3/393 |
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| author | Linyong Shen Jiaqiang Yu Yaowen Ge Hui Li Yumao Li Zhiping Cao Peng Luan Fan Xiao Haihe Gao Hui Zhang |
| author_facet | Linyong Shen Jiaqiang Yu Yaowen Ge Hui Li Yumao Li Zhiping Cao Peng Luan Fan Xiao Haihe Gao Hui Zhang |
| author_sort | Linyong Shen |
| collection | DOAJ |
| description | This study aims to identify molecular marker loci that could be applied in broiler breeding programs. In this study, we used public databases to locate the <i>Transcription factor 21</i> (<i>TCF21</i>) gene that affected the economically important traits in broilers. Ten single nucleotide polymorphisms were detected in the <i>TCF21</i> gene by monoclonal sequencing. The polymorphisms of these 10 SNPs in the <i>TCF21</i> gene were significantly associated (<i>p</i> < 0.05) with multiple growth and body composition traits. Furthermore, the <i>TT</i> genotype of g.-911T>G was identified to significantly increase the heart weight trait without affecting the negative traits, such as abdominal fat and reproduction by multiple methods. Thus, it was speculated that the g.-911T>G identified in the <i>TCF21</i> gene might be used in marker-assisted selection in the broiler breeding program. |
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| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-10T00:17:09Z |
| publishDate | 2022-02-01 |
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| spelling | doaj.art-9a481cc75d6f48f1a26c029fae3d7fbe2023-11-23T15:49:06ZengMDPI AGAnimals2076-26152022-02-0112339310.3390/ani12030393Associations of Transcription Factor 21 Gene Polymorphisms with the Growth and Body Composition Traits in BroilersLinyong Shen0Jiaqiang Yu1Yaowen Ge2Hui Li3Yumao Li4Zhiping Cao5Peng Luan6Fan Xiao7Haihe Gao8Hui Zhang9Key Laboratory of Chicken Genetics and Breeding, Ministry of Agriculture and Rural Affairs, Key Laboratory of Animal Genetics, Breeding and Reproduction, Education Department of Heilongjiang Province, College of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, ChinaForest Investigating and Planning Institute of Daxinganling, Yakshi 022150, ChinaKey Laboratory of Chicken Genetics and Breeding, Ministry of Agriculture and Rural Affairs, Key Laboratory of Animal Genetics, Breeding and Reproduction, Education Department of Heilongjiang Province, College of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, ChinaKey Laboratory of Chicken Genetics and Breeding, Ministry of Agriculture and Rural Affairs, Key Laboratory of Animal Genetics, Breeding and Reproduction, Education Department of Heilongjiang Province, College of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, ChinaKey Laboratory of Chicken Genetics and Breeding, Ministry of Agriculture and Rural Affairs, Key Laboratory of Animal Genetics, Breeding and Reproduction, Education Department of Heilongjiang Province, College of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, ChinaKey Laboratory of Chicken Genetics and Breeding, Ministry of Agriculture and Rural Affairs, Key Laboratory of Animal Genetics, Breeding and Reproduction, Education Department of Heilongjiang Province, College of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, ChinaKey Laboratory of Chicken Genetics and Breeding, Ministry of Agriculture and Rural Affairs, Key Laboratory of Animal Genetics, Breeding and Reproduction, Education Department of Heilongjiang Province, College of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, ChinaFujian Sunnzer Biotechnology Development Co., Ltd., Nanping 354100, ChinaFujian Sunnzer Biotechnology Development Co., Ltd., Nanping 354100, ChinaKey Laboratory of Chicken Genetics and Breeding, Ministry of Agriculture and Rural Affairs, Key Laboratory of Animal Genetics, Breeding and Reproduction, Education Department of Heilongjiang Province, College of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, ChinaThis study aims to identify molecular marker loci that could be applied in broiler breeding programs. In this study, we used public databases to locate the <i>Transcription factor 21</i> (<i>TCF21</i>) gene that affected the economically important traits in broilers. Ten single nucleotide polymorphisms were detected in the <i>TCF21</i> gene by monoclonal sequencing. The polymorphisms of these 10 SNPs in the <i>TCF21</i> gene were significantly associated (<i>p</i> < 0.05) with multiple growth and body composition traits. Furthermore, the <i>TT</i> genotype of g.-911T>G was identified to significantly increase the heart weight trait without affecting the negative traits, such as abdominal fat and reproduction by multiple methods. Thus, it was speculated that the g.-911T>G identified in the <i>TCF21</i> gene might be used in marker-assisted selection in the broiler breeding program.https://www.mdpi.com/2076-2615/12/3/393single nucleotide polymorphismmarker-assisted selectionbroiler chicken |
| spellingShingle | Linyong Shen Jiaqiang Yu Yaowen Ge Hui Li Yumao Li Zhiping Cao Peng Luan Fan Xiao Haihe Gao Hui Zhang Associations of Transcription Factor 21 Gene Polymorphisms with the Growth and Body Composition Traits in Broilers Animals single nucleotide polymorphism marker-assisted selection broiler chicken |
| title | Associations of Transcription Factor 21 Gene Polymorphisms with the Growth and Body Composition Traits in Broilers |
| title_full | Associations of Transcription Factor 21 Gene Polymorphisms with the Growth and Body Composition Traits in Broilers |
| title_fullStr | Associations of Transcription Factor 21 Gene Polymorphisms with the Growth and Body Composition Traits in Broilers |
| title_full_unstemmed | Associations of Transcription Factor 21 Gene Polymorphisms with the Growth and Body Composition Traits in Broilers |
| title_short | Associations of Transcription Factor 21 Gene Polymorphisms with the Growth and Body Composition Traits in Broilers |
| title_sort | associations of transcription factor 21 gene polymorphisms with the growth and body composition traits in broilers |
| topic | single nucleotide polymorphism marker-assisted selection broiler chicken |
| url | https://www.mdpi.com/2076-2615/12/3/393 |
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