Bone Health Impairment in Patients with Hemoglobinopathies: From Biological Bases to New Possible Therapeutic Strategies

Bone Health Impairment in Patients with Hemoglobinopathies: From Biological Bases to New Possible Therapeutic Strategies

Hemoglobinopathies are monogenic disorders affecting hemoglobin synthesis. Thalassemia and sickle cell disease (SCD) are considered the two major hemoglobinopathies. Thalassemia is a genetic disorder and one of the major hemoglobinopathies determined by an impairment of globin chain production, whic...

Full description

Bibliographic Details
Main Authors:	Alessandra Di Paola, Maria Maddalena Marrapodi, Martina Di Martino, Giulia Giliberti, Giuseppe Di Feo, Deeksha Rana, Shakeel Ahmed, Maura Argenziano, Francesca Rossi, Domenico Roberti
Format:	Article
Language:	English
Published:	MDPI AG 2024-03-01
Series:	International Journal of Molecular Sciences
Subjects:	hemoglobinopathies thalassemia sickle cell disease (SCD) alteration of bone metabolism osteoporosis (OP)
Online Access:	https://www.mdpi.com/1422-0067/25/5/2902

Similar Items

Epidemiological and molecular study of hemoglobinopathies in Mauritanian patients
by: Taher Mahmoud, et al.
Published: (2022-10-01)

Iowa Newborn Screening Program Experience with Hemoglobinopathy Screening over the Last Two Decades and Its Increasing Global Relevance
by: Ryan Jilek, et al.
Published: (2024-03-01)

Type and frequency of hemoglobinopathies, diagnosed in the area of Karachi, in Pakistan
by: Shaista Shabbir, et al.
Published: (2016-12-01)

Iron overload and chelation therapy in hemoglobinopathies
by: Rayan Bou-Fakhredin, et al.
Published: (2018-04-01)

HLA haplotype frequencies and diversity in patients with hemoglobinopathies
by: Graziana M. Scigliuolo, et al.
Published: (2023-11-01)

Assessment of Sleep Disorders in Children with Transfusion-Dependent Hemoglobinopathies
by: Ahmed Masoud Ali, et al.
Published: (2023-07-01)

Estimation of the prevalence of Hemoglobinopathies in Erbil governorate, Kurdistan region of Iraq
by: Sarkar S Aziz, et al.
Published: (2022-01-01)

Diagnostic strategies in hemoglobinopathy testing, the role of a reference laboratory in the USA
by: Jennifer L. Oliveira
Published: (2018-04-01)

Prevention of hemoglobinopathies in Saudi Arabia: efficacy of national premarital screening and the feasibility of preimplantation genetic diagnosis
by: Muhammad Umair, et al.
Published: (2020-12-01)

Thalassemias and Other Hemoglobinopathies in Former Yugoslavia
by: Efremov G
Published: (2008-01-01)

An Innovative Multilevel Test for Hemoglobinopathies: TGA/Chemometrics Simultaneously Identifies and Classifies Sickle Cell Disease From Thalassemia
by: Roberta Risoluti, et al.
Published: (2020-07-01)

The Prevalence of β-Thalassemia and Other Hemoglobinopathies in Kuwaiti Premarital Screening Program: An 11-Year Experience
by: Najat Rouh AlDeen, et al.
Published: (2021-09-01)

Precision Editing as a Therapeutic Approach for β-Hemoglobinopathies
by: Kiriaki Paschoudi, et al.
Published: (2023-05-01)

Hemoglobinopathies in Iran: An Updated Review
by: Abolfazl Nasiri, et al.
Published: (2020-04-01)

Red blood cell indices in different hemoglobinopathies: A cross-sectional study in Eastern India
by: Ayandip Nandi, et al.
Published: (2024-01-01)

Comparison of biochemical parameters of prevalent hemoglobinopathies with healthy individuals
by: Emrah Yerlikaya, et al.
Published: (2020-09-01)

Pattern of hemoglobinopathy among the young tribes of West Bengal: A completely different scenario from Rest of India
by: Jyoti Shaw, et al.
Published: (2023-01-01)

First and Second Level Haemoglobinopathies Diagnosis: Best Practices of the Italian Society of Thalassemia and Haemoglobinopathies (SITE)
by: Giorgia Mandrile, et al.
Published: (2022-09-01)

Prevalence of Co-Inheritance of Alpha-Thalassemia with Beta-Thalassemia and Beta-Hemoglobinopathy in Ahvaz City
by: Najmaddin Saki, et al.
Published: (2013-09-01)

Erythrocytapheresis in Children and Young Adults with Hemoglobinopathies and Iron Overload in Need of Iron Chelation Therapy
by: Jessica van Hattem, et al.
Published: (2023-09-01)

Spectrum of types of thalassemias and hemoglobinopathies: study in a tertiary level children hospital in Bangladesh
by: Waqar A. Khan, et al.
Published: (2017-05-01)

Genética das doenças hematológicas: as hemoglobinopatias hereditárias The genetics of blood disorders: hereditary hemoglobinopathies
by: Maria de Fátima Sonati, et al.
Published: (2008-08-01)

The Prevalence of Anemia and Hemoglobinopathies in the Hematologic Clinics of the Kermanshah Province, Western Iran
by: Mehrdad Payandeh, et al.
Published: (2014-06-01)

12th International Conference on Thalassemia and the Haemoglobinopathies, 11-14 May 2011, Antalya, Turkey
by: Guest Editors: Aurelio Maggio, Duran Canatan, Androulla Eleftheriou
Published: (2011-05-01)

Comparison of Capillary Zone Electrophoresis with High-pressure Liquid Chromatography in the Evaluation of Hemoglobinopathies
by: Özlem Çakır Madenci, et al.
Published: (2023-12-01)

The blood count as a compass to navigate in the ever-changing landscape of the carrier state of hemoglobinopathies: a single-center Italian experience
by: Silvio Marchesani, et al.
Published: (2023-10-01)

Gene Therapy for β-Hemoglobinopathies: From Discovery to Clinical Trials
by: Eva Eugenie Rose Segura, et al.
Published: (2023-03-01)

Spectrum of Thalassemia and Hemoglobinopathy Using Capillary Zone Electrophoresis: A Facility-Based Single Centred Study at icddr,b in Bangladesh
by: Anamul Hasan, et al.
Published: (2023-05-01)

Osteoporosis in thalassaemia
by: Ersi Voskaridou, et al.
Published: (2018-04-01)

New challenges in diagnosis of haemoglobinopathies: Migration of populations
by: John Old, et al.
Published: (2018-04-01)

Quality of life: Transfusion dependent thalassemia vs non-transfusion dependent thalassemia
by: Mehran Karimi, et al.
Published: (2018-04-01)

Patients as equal partners in decision-making: The global reality
by: Anubha Taneja Mukherjee
Published: (2018-04-01)

Diagnosis of haemoglobinopathies: New scientific advances
by: Cornelis L. Harteveld
Published: (2018-04-01)

Thalime: A mobile app designed just for patients and their families
by: Hatley Forrest McMicking
Published: (2018-04-01)

National policies in ensuring access to quality and safety of drugs: A challenge or a prerequisite
by: M. Hadipour Dehshal, et al.
Published: (2018-04-01)

Safety and efficacy of drugs: What do I need to know?
by: Mahmoud Hadipour Dehshal
Published: (2018-04-01)

Migration: The aftershocks to the provision of healthcare
by: Stephan Lobitz
Published: (2018-04-01)

3rd Pan-European Conference on Haemoglobinopathies and Rare Anaemias, 24-26 October 2012, Limassol - Cyprus
by: Androulla Eleftheriou, et al.
Published: (2012-12-01)

The role of the clinical nurse specialist in haemoglobinopathies
by: Bernadette Hylton
Published: (2018-04-01)

TIF conference presentation in detail
by: Barrister Abid Waheed Shaikh
Published: (2018-04-01)