Chinese herbal prescriptions for COVID-19 management: Special reference to Taiwan Chingguan Yihau (NRICM101)

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a strain of coronavirus that causes COVID-19 (coronavirus disease 2019), the respiratory illness responsible for the ongoing COVID-19 pandemic. As at June 2022, increasing numbers of newly diagnosed COVID-19-associated pneumonia cases w...

Full description

Bibliographic Details
Main Authors: Yi-Chang Su, Guan-Jhong Huang, Jaung-Geng Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.928106/full
_version_ 1817969280490143744
author Yi-Chang Su
Guan-Jhong Huang
Guan-Jhong Huang
Jaung-Geng Lin
author_facet Yi-Chang Su
Guan-Jhong Huang
Guan-Jhong Huang
Jaung-Geng Lin
author_sort Yi-Chang Su
collection DOAJ
description Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a strain of coronavirus that causes COVID-19 (coronavirus disease 2019), the respiratory illness responsible for the ongoing COVID-19 pandemic. As at June 2022, increasing numbers of newly diagnosed COVID-19-associated pneumonia cases worldwide have attracted close attention from the international community. The present review analyzes and summarizes the treatment of COVID-19 with traditional Chinese medicine (TCM). A systematic analysis of the efficacies and benefits of TCM for the treatment of COVID-19 was performed, and the mechanisms underlying such treatment are summarized. This analysis of the literature highlights the potential of TCM to prevent and treat COVID-19 via antiviral, anti-inflammatory and immunomodulatory activities, with evidence showing that many TCM components act upon multiple targets and pathways. Famous TCM formulas include Qing-Fei-Pai-Du-Tang (QFPDT), Lianhuaqingwen Capsule (LHC), Taiwan Chingguan Yihau (NRICM101), and Jing Si herbal drink (JSHD). In particular, the botanical preparation NRICM101 was developed in 2020 for use in viral respiratory tract infections and is recommended for treating non-severe and mild COVID-19 infections. NRICM101 has been adopted for use in Taiwan for the clinical treatment of COVID-19. The common components and active ingredients of 10 TCM preparations have been analyzed for the most promising substances. This review aims to provide reliable evidence demonstrating the therapeutic efficacy of TCM substances in support of their further development against novel coronavirus infectious diseases in Taiwan.
first_indexed 2024-04-13T20:19:16Z
format Article
id doaj.art-9a4b2ffbc06046e3a6753bbca2e61859
institution Directory Open Access Journal
issn 1663-9812
language English
last_indexed 2024-04-13T20:19:16Z
publishDate 2022-10-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Pharmacology
spelling doaj.art-9a4b2ffbc06046e3a6753bbca2e618592022-12-22T02:31:36ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122022-10-011310.3389/fphar.2022.928106928106Chinese herbal prescriptions for COVID-19 management: Special reference to Taiwan Chingguan Yihau (NRICM101)Yi-Chang Su0Guan-Jhong Huang1Guan-Jhong Huang2Jaung-Geng Lin3National Research Institute of Chinese Medicine, Ministry of Health and Welfare, Taipei, TaiwanDepartment of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, College of Chinese Medicine, China Medical University, Taichung, TaiwanDepartment of Food Nutrition and Healthy Biotechnology, Asia University, Taichung, TaiwanSchool of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, TaiwanSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a strain of coronavirus that causes COVID-19 (coronavirus disease 2019), the respiratory illness responsible for the ongoing COVID-19 pandemic. As at June 2022, increasing numbers of newly diagnosed COVID-19-associated pneumonia cases worldwide have attracted close attention from the international community. The present review analyzes and summarizes the treatment of COVID-19 with traditional Chinese medicine (TCM). A systematic analysis of the efficacies and benefits of TCM for the treatment of COVID-19 was performed, and the mechanisms underlying such treatment are summarized. This analysis of the literature highlights the potential of TCM to prevent and treat COVID-19 via antiviral, anti-inflammatory and immunomodulatory activities, with evidence showing that many TCM components act upon multiple targets and pathways. Famous TCM formulas include Qing-Fei-Pai-Du-Tang (QFPDT), Lianhuaqingwen Capsule (LHC), Taiwan Chingguan Yihau (NRICM101), and Jing Si herbal drink (JSHD). In particular, the botanical preparation NRICM101 was developed in 2020 for use in viral respiratory tract infections and is recommended for treating non-severe and mild COVID-19 infections. NRICM101 has been adopted for use in Taiwan for the clinical treatment of COVID-19. The common components and active ingredients of 10 TCM preparations have been analyzed for the most promising substances. This review aims to provide reliable evidence demonstrating the therapeutic efficacy of TCM substances in support of their further development against novel coronavirus infectious diseases in Taiwan.https://www.frontiersin.org/articles/10.3389/fphar.2022.928106/fullSARS-CoV-2antivirusanti-inflammationtraditional Chinese medicineviral infection
spellingShingle Yi-Chang Su
Guan-Jhong Huang
Guan-Jhong Huang
Jaung-Geng Lin
Chinese herbal prescriptions for COVID-19 management: Special reference to Taiwan Chingguan Yihau (NRICM101)
Frontiers in Pharmacology
SARS-CoV-2
antivirus
anti-inflammation
traditional Chinese medicine
viral infection
title Chinese herbal prescriptions for COVID-19 management: Special reference to Taiwan Chingguan Yihau (NRICM101)
title_full Chinese herbal prescriptions for COVID-19 management: Special reference to Taiwan Chingguan Yihau (NRICM101)
title_fullStr Chinese herbal prescriptions for COVID-19 management: Special reference to Taiwan Chingguan Yihau (NRICM101)
title_full_unstemmed Chinese herbal prescriptions for COVID-19 management: Special reference to Taiwan Chingguan Yihau (NRICM101)
title_short Chinese herbal prescriptions for COVID-19 management: Special reference to Taiwan Chingguan Yihau (NRICM101)
title_sort chinese herbal prescriptions for covid 19 management special reference to taiwan chingguan yihau nricm101
topic SARS-CoV-2
antivirus
anti-inflammation
traditional Chinese medicine
viral infection
url https://www.frontiersin.org/articles/10.3389/fphar.2022.928106/full
work_keys_str_mv AT yichangsu chineseherbalprescriptionsforcovid19managementspecialreferencetotaiwanchingguanyihaunricm101
AT guanjhonghuang chineseherbalprescriptionsforcovid19managementspecialreferencetotaiwanchingguanyihaunricm101
AT guanjhonghuang chineseherbalprescriptionsforcovid19managementspecialreferencetotaiwanchingguanyihaunricm101
AT jaunggenglin chineseherbalprescriptionsforcovid19managementspecialreferencetotaiwanchingguanyihaunricm101