CADASIL presenting as late‐onset mania with anosognosia

Abstract The diagnosis of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) should be considered in patients with late‐onset personality change and mania. However, neuropsychological deficits precipitated by the disorder pose significant challenges...

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Main Authors: Manik Uppal, Dora Kanellopoulos, Nabil Kotbi
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Clinical Case Reports
Subjects:
Online Access:https://doi.org/10.1002/ccr3.2594
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author Manik Uppal
Dora Kanellopoulos
Nabil Kotbi
author_facet Manik Uppal
Dora Kanellopoulos
Nabil Kotbi
author_sort Manik Uppal
collection DOAJ
description Abstract The diagnosis of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) should be considered in patients with late‐onset personality change and mania. However, neuropsychological deficits precipitated by the disorder pose significant challenges to recognition and appropriate management of CADASIL in susceptible patients.
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spelling doaj.art-9a4db00fb36c4004a357265a2a42da6a2022-12-21T23:54:26ZengWileyClinical Case Reports2050-09042020-01-0181475010.1002/ccr3.2594CADASIL presenting as late‐onset mania with anosognosiaManik Uppal0Dora Kanellopoulos1Nabil Kotbi2Weill Cornell Medical College New York Presbyterian Hospital New York NY USAWeill Cornell Medical College New York Presbyterian Hospital New York NY USAWeill Cornell Medical College New York Presbyterian Hospital New York NY USAAbstract The diagnosis of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) should be considered in patients with late‐onset personality change and mania. However, neuropsychological deficits precipitated by the disorder pose significant challenges to recognition and appropriate management of CADASIL in susceptible patients.https://doi.org/10.1002/ccr3.2594anosognosiabipolar disorderCADASILpersonality change
spellingShingle Manik Uppal
Dora Kanellopoulos
Nabil Kotbi
CADASIL presenting as late‐onset mania with anosognosia
Clinical Case Reports
anosognosia
bipolar disorder
CADASIL
personality change
title CADASIL presenting as late‐onset mania with anosognosia
title_full CADASIL presenting as late‐onset mania with anosognosia
title_fullStr CADASIL presenting as late‐onset mania with anosognosia
title_full_unstemmed CADASIL presenting as late‐onset mania with anosognosia
title_short CADASIL presenting as late‐onset mania with anosognosia
title_sort cadasil presenting as late onset mania with anosognosia
topic anosognosia
bipolar disorder
CADASIL
personality change
url https://doi.org/10.1002/ccr3.2594
work_keys_str_mv AT manikuppal cadasilpresentingaslateonsetmaniawithanosognosia
AT dorakanellopoulos cadasilpresentingaslateonsetmaniawithanosognosia
AT nabilkotbi cadasilpresentingaslateonsetmaniawithanosognosia