Clinical Efficiency of Application of Intravenous Immunoglobulin in Pregnant Women with Intrauterine Infection
The problem of intrauterine infection (IUI) is still relevant today. Ineffective treatment of this pathology is associated with physiological decline of the immunity in these patients. We have proposed the additional use of intravenous immunoglobulin for the treatment of pregnant women with IUI. The...
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| Format: | Article |
| Language: | English |
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Zaslavsky O.Yu.
2016-02-01
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| Series: | Aktualʹnaâ Infektologiâ |
| Subjects: | |
| Online Access: | http://ai.zaslavsky.com.ua/article/view/74533 |
| _version_ | 1818997589559738368 |
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| author | O.L. Ishchenko I.P. Krokhmal S.M. Serhiienko I.O. Kovtoniuk |
| author_facet | O.L. Ishchenko I.P. Krokhmal S.M. Serhiienko I.O. Kovtoniuk |
| author_sort | O.L. Ishchenko |
| collection | DOAJ |
| description | The problem of intrauterine infection (IUI) is still relevant today. Ineffective treatment of this pathology is associated with physiological decline of the immunity in these patients. We have proposed the additional use of intravenous immunoglobulin for the treatment of pregnant women with IUI. There were examined 75 patients with IUI, which was diagnosed in the II trimester. The I group consisted of 40 individuals who received conventional treatment, the II group was formed from 35 women who additionally received intravenous immunoglobulin. On the background of IUI, pregnancy was characterized by an increased incidence of threatened miscarriage and premature labor, gestosis and placental dysfunction; during delivery, premature rupture of amniotic membrane and fetal distress were more common. These patients had placenta with both ultrasonic and histological signs of infection. Among newborns, there was a significant increase in the incidence of pathology associated with intrauterine infection. Additional use of intravenous immunoglobulin in the treatment of IUI during the II trimester of pregnancy in comparison with conventional therapy leads to a significant reduction in the incidence of both obstetric complications and perinatal pathology. |
| first_indexed | 2024-12-20T21:48:02Z |
| format | Article |
| id | doaj.art-9a577a457f2548ceaee29934f1824f9d |
| institution | Directory Open Access Journal |
| issn | 2312-413X 2312-4148 |
| language | English |
| last_indexed | 2024-12-20T21:48:02Z |
| publishDate | 2016-02-01 |
| publisher | Zaslavsky O.Yu. |
| record_format | Article |
| series | Aktualʹnaâ Infektologiâ |
| spelling | doaj.art-9a577a457f2548ceaee29934f1824f9d2022-12-21T19:25:38ZengZaslavsky O.Yu.Aktualʹnaâ Infektologiâ2312-413X2312-41482016-02-0141.10323710.22141/2312-413x.1.10.2016.7453374533Clinical Efficiency of Application of Intravenous Immunoglobulin in Pregnant Women with Intrauterine InfectionO.L. Ishchenko0I.P. Krokhmal1S.M. Serhiienko2I.O. Kovtoniuk3State Institution «Luhansk State Medical University», Luhansk, UkraineState Institution «Luhansk State Medical University», Luhansk, UkraineState Institution «Luhansk State Medical University», Luhansk, UkraineState Institution «Luhansk State Medical University», Luhansk, UkraineThe problem of intrauterine infection (IUI) is still relevant today. Ineffective treatment of this pathology is associated with physiological decline of the immunity in these patients. We have proposed the additional use of intravenous immunoglobulin for the treatment of pregnant women with IUI. There were examined 75 patients with IUI, which was diagnosed in the II trimester. The I group consisted of 40 individuals who received conventional treatment, the II group was formed from 35 women who additionally received intravenous immunoglobulin. On the background of IUI, pregnancy was characterized by an increased incidence of threatened miscarriage and premature labor, gestosis and placental dysfunction; during delivery, premature rupture of amniotic membrane and fetal distress were more common. These patients had placenta with both ultrasonic and histological signs of infection. Among newborns, there was a significant increase in the incidence of pathology associated with intrauterine infection. Additional use of intravenous immunoglobulin in the treatment of IUI during the II trimester of pregnancy in comparison with conventional therapy leads to a significant reduction in the incidence of both obstetric complications and perinatal pathology.http://ai.zaslavsky.com.ua/article/view/74533intravenous immunoglobulinintrauterine infectionpregnancy complicationsneonatal pathology |
| spellingShingle | O.L. Ishchenko I.P. Krokhmal S.M. Serhiienko I.O. Kovtoniuk Clinical Efficiency of Application of Intravenous Immunoglobulin in Pregnant Women with Intrauterine Infection Aktualʹnaâ Infektologiâ intravenous immunoglobulin intrauterine infection pregnancy complications neonatal pathology |
| title | Clinical Efficiency of Application of Intravenous Immunoglobulin in Pregnant Women with Intrauterine Infection |
| title_full | Clinical Efficiency of Application of Intravenous Immunoglobulin in Pregnant Women with Intrauterine Infection |
| title_fullStr | Clinical Efficiency of Application of Intravenous Immunoglobulin in Pregnant Women with Intrauterine Infection |
| title_full_unstemmed | Clinical Efficiency of Application of Intravenous Immunoglobulin in Pregnant Women with Intrauterine Infection |
| title_short | Clinical Efficiency of Application of Intravenous Immunoglobulin in Pregnant Women with Intrauterine Infection |
| title_sort | clinical efficiency of application of intravenous immunoglobulin in pregnant women with intrauterine infection |
| topic | intravenous immunoglobulin intrauterine infection pregnancy complications neonatal pathology |
| url | http://ai.zaslavsky.com.ua/article/view/74533 |
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