THE ROLE OF HUMAN PAPILLOMAVIRUS IN DEVELOPMENT OF OROPHARYNGEAL CANCER
This article provides review of foreign literature on the problem of HPV-associated oropharyngeal cancer incidence. Epidemiological researches demonstrate increase of incidence of oropharyngeal squamous cell carcinoma (OPSCC) especially among white men of middle age. Such growth of oropharyngeal can...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Ministry of Healthcare of the Russian Federation. “Kuban State Medical University”
2016-10-01
|
| Series: | Кубанский научный медицинский вестник |
| Subjects: | |
| Online Access: | https://ksma.elpub.ru/jour/article/view/609 |
| _version_ | 1797295556417028096 |
|---|---|
| author | A. I. Stukan V. N. Bodnya E. V. Dulina A. A. Leonov V. I. Aleksandrov |
| author_facet | A. I. Stukan V. N. Bodnya E. V. Dulina A. A. Leonov V. I. Aleksandrov |
| author_sort | A. I. Stukan |
| collection | DOAJ |
| description | This article provides review of foreign literature on the problem of HPV-associated oropharyngeal cancer incidence. Epidemiological researches demonstrate increase of incidence of oropharyngeal squamous cell carcinoma (OPSCC) especially among white men of middle age. Such growth of oropharyngeal cancer incidence is associated with human papilloma virus type 16 (HPV 16). The p16 - protein expression is the marker of HPV DNA integration into human nuclear DNA. It is suggested that detection of tumor HPV-status can predict prognosis and develop preventive measures. |
| first_indexed | 2024-03-07T21:49:40Z |
| format | Article |
| id | doaj.art-9a5948f3b2da43f3989bf19fdd895f92 |
| institution | Directory Open Access Journal |
| issn | 1608-6228 2541-9544 |
| language | Russian |
| last_indexed | 2024-03-07T21:49:40Z |
| publishDate | 2016-10-01 |
| publisher | Ministry of Healthcare of the Russian Federation. “Kuban State Medical University” |
| record_format | Article |
| series | Кубанский научный медицинский вестник |
| spelling | doaj.art-9a5948f3b2da43f3989bf19fdd895f922024-02-25T10:57:19ZrusMinistry of Healthcare of the Russian Federation. “Kuban State Medical University”Кубанский научный медицинский вестник1608-62282541-95442016-10-01515415710.25207/1608-6228-2016-5-154-157609THE ROLE OF HUMAN PAPILLOMAVIRUS IN DEVELOPMENT OF OROPHARYNGEAL CANCERA. I. Stukan0V. N. Bodnya1E. V. Dulina2A. A. Leonov3V. I. Aleksandrov4ГБОУ ВПО Куб ГМУ Минздрава РоссииГБОУ ВПО Куб ГМУ Минздрава РоссииГБУЗ «Клинический онкологический диспансер» № 1 министерства здравоохранения Краснодарского краяГБУЗ «Клинический онкологический диспансер» № 1 министерства здравоохранения Краснодарского краяГБУЗ «Клинический онкологический диспансер» № 1 министерства здравоохранения Краснодарского краяThis article provides review of foreign literature on the problem of HPV-associated oropharyngeal cancer incidence. Epidemiological researches demonstrate increase of incidence of oropharyngeal squamous cell carcinoma (OPSCC) especially among white men of middle age. Such growth of oropharyngeal cancer incidence is associated with human papilloma virus type 16 (HPV 16). The p16 - protein expression is the marker of HPV DNA integration into human nuclear DNA. It is suggested that detection of tumor HPV-status can predict prognosis and develop preventive measures.https://ksma.elpub.ru/jour/article/view/609рак ротоглоткивпч-позитивная офпккэкспрессия белка р16oropharyngeal cancerhpv-positive opsccexpression of p16 protein |
| spellingShingle | A. I. Stukan V. N. Bodnya E. V. Dulina A. A. Leonov V. I. Aleksandrov THE ROLE OF HUMAN PAPILLOMAVIRUS IN DEVELOPMENT OF OROPHARYNGEAL CANCER Кубанский научный медицинский вестник рак ротоглотки впч-позитивная офпкк экспрессия белка р16 oropharyngeal cancer hpv-positive opscc expression of p16 protein |
| title | THE ROLE OF HUMAN PAPILLOMAVIRUS IN DEVELOPMENT OF OROPHARYNGEAL CANCER |
| title_full | THE ROLE OF HUMAN PAPILLOMAVIRUS IN DEVELOPMENT OF OROPHARYNGEAL CANCER |
| title_fullStr | THE ROLE OF HUMAN PAPILLOMAVIRUS IN DEVELOPMENT OF OROPHARYNGEAL CANCER |
| title_full_unstemmed | THE ROLE OF HUMAN PAPILLOMAVIRUS IN DEVELOPMENT OF OROPHARYNGEAL CANCER |
| title_short | THE ROLE OF HUMAN PAPILLOMAVIRUS IN DEVELOPMENT OF OROPHARYNGEAL CANCER |
| title_sort | role of human papillomavirus in development of oropharyngeal cancer |
| topic | рак ротоглотки впч-позитивная офпкк экспрессия белка р16 oropharyngeal cancer hpv-positive opscc expression of p16 protein |
| url | https://ksma.elpub.ru/jour/article/view/609 |
| work_keys_str_mv | AT aistukan theroleofhumanpapillomavirusindevelopmentoforopharyngealcancer AT vnbodnya theroleofhumanpapillomavirusindevelopmentoforopharyngealcancer AT evdulina theroleofhumanpapillomavirusindevelopmentoforopharyngealcancer AT aaleonov theroleofhumanpapillomavirusindevelopmentoforopharyngealcancer AT vialeksandrov theroleofhumanpapillomavirusindevelopmentoforopharyngealcancer AT aistukan roleofhumanpapillomavirusindevelopmentoforopharyngealcancer AT vnbodnya roleofhumanpapillomavirusindevelopmentoforopharyngealcancer AT evdulina roleofhumanpapillomavirusindevelopmentoforopharyngealcancer AT aaleonov roleofhumanpapillomavirusindevelopmentoforopharyngealcancer AT vialeksandrov roleofhumanpapillomavirusindevelopmentoforopharyngealcancer |