The Octopus Trap of Takotsubo and Stroke: Genetics, Biomarkers and Clinical Management
Takotsubo cardiomyopathy (TC) is a reversible cardiomyopathy mimicking an acute coronary syndrome, usually observed in response to acute stress situations. The association between acute ischemic stroke and TC is already known, since it has been previously reported that ischemic stroke can be both a...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-07-01
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| Series: | Journal of Personalized Medicine |
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| Online Access: | https://www.mdpi.com/2075-4426/12/8/1244 |
| _version_ | 1797409409740046336 |
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| author | Isabella Canavero Nicola Rifino Maurizio Bussotti Tatiana Carrozzini Antonella Potenza Gemma Gorla Giuliana Pollaci Benedetta Storti Eugenio Agostino Parati Laura Gatti Anna Bersano |
| author_facet | Isabella Canavero Nicola Rifino Maurizio Bussotti Tatiana Carrozzini Antonella Potenza Gemma Gorla Giuliana Pollaci Benedetta Storti Eugenio Agostino Parati Laura Gatti Anna Bersano |
| author_sort | Isabella Canavero |
| collection | DOAJ |
| description | Takotsubo cardiomyopathy (TC) is a reversible cardiomyopathy mimicking an acute coronary syndrome, usually observed in response to acute stress situations. The association between acute ischemic stroke and TC is already known, since it has been previously reported that ischemic stroke can be both a consequence and a potential cause of TC. However, the precise pathophysiological mechanism linking the two conditions is still poorly understood. The aim of our review is to expand insights regarding the genetic susceptibility and available specific biomarkers of TC and to investigate the clinical profile and outcomes of patients with TC and stroke. Since evidence and trials on TC and stroke are currently lacking, this paper aims to fill a substantial gap in the literature about the relationship between these pathologies. |
| first_indexed | 2024-03-09T04:15:14Z |
| format | Article |
| id | doaj.art-9a59a1a822524edbb3c4558232dea8ff |
| institution | Directory Open Access Journal |
| issn | 2075-4426 |
| language | English |
| last_indexed | 2024-03-09T04:15:14Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Personalized Medicine |
| spelling | doaj.art-9a59a1a822524edbb3c4558232dea8ff2023-12-03T13:55:54ZengMDPI AGJournal of Personalized Medicine2075-44262022-07-01128124410.3390/jpm12081244The Octopus Trap of Takotsubo and Stroke: Genetics, Biomarkers and Clinical ManagementIsabella Canavero0Nicola Rifino1Maurizio Bussotti2Tatiana Carrozzini3Antonella Potenza4Gemma Gorla5Giuliana Pollaci6Benedetta Storti7Eugenio Agostino Parati8Laura Gatti9Anna Bersano10Cerebrovascular Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133 Milan, ItalyCerebrovascular Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133 Milan, ItalyCardiology Rehabilitative Unit, IRCCS Istituti Clinici Scientifici Maugeri Clinical Scientific Institutes, 20138 Milan, ItalyCerebrovascular Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133 Milan, ItalyCerebrovascular Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133 Milan, ItalyCerebrovascular Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133 Milan, ItalyCerebrovascular Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133 Milan, ItalyCerebrovascular Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133 Milan, ItalyNeurology Rehabilitative Unit, IRCCS Istituti Clinici Scientifici Maugeri Clinical Scientific Institutes, 20138 Milan, ItalyCerebrovascular Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133 Milan, ItalyCerebrovascular Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133 Milan, ItalyTakotsubo cardiomyopathy (TC) is a reversible cardiomyopathy mimicking an acute coronary syndrome, usually observed in response to acute stress situations. The association between acute ischemic stroke and TC is already known, since it has been previously reported that ischemic stroke can be both a consequence and a potential cause of TC. However, the precise pathophysiological mechanism linking the two conditions is still poorly understood. The aim of our review is to expand insights regarding the genetic susceptibility and available specific biomarkers of TC and to investigate the clinical profile and outcomes of patients with TC and stroke. Since evidence and trials on TC and stroke are currently lacking, this paper aims to fill a substantial gap in the literature about the relationship between these pathologies.https://www.mdpi.com/2075-4426/12/8/1244Takotsubo cardiomyopathystrokeacute stressgenetic susceptibilitybiomarkers |
| spellingShingle | Isabella Canavero Nicola Rifino Maurizio Bussotti Tatiana Carrozzini Antonella Potenza Gemma Gorla Giuliana Pollaci Benedetta Storti Eugenio Agostino Parati Laura Gatti Anna Bersano The Octopus Trap of Takotsubo and Stroke: Genetics, Biomarkers and Clinical Management Journal of Personalized Medicine Takotsubo cardiomyopathy stroke acute stress genetic susceptibility biomarkers |
| title | The Octopus Trap of Takotsubo and Stroke: Genetics, Biomarkers and Clinical Management |
| title_full | The Octopus Trap of Takotsubo and Stroke: Genetics, Biomarkers and Clinical Management |
| title_fullStr | The Octopus Trap of Takotsubo and Stroke: Genetics, Biomarkers and Clinical Management |
| title_full_unstemmed | The Octopus Trap of Takotsubo and Stroke: Genetics, Biomarkers and Clinical Management |
| title_short | The Octopus Trap of Takotsubo and Stroke: Genetics, Biomarkers and Clinical Management |
| title_sort | octopus trap of takotsubo and stroke genetics biomarkers and clinical management |
| topic | Takotsubo cardiomyopathy stroke acute stress genetic susceptibility biomarkers |
| url | https://www.mdpi.com/2075-4426/12/8/1244 |
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