Vitamin D in acutely ill patients
Objective To investigate 25(OH)D 3 levels and their relationship to survival in a cohort of acutely ill patients on admission to an intensive care unit. Methods This study enrolled acutely ill patients at admission to an intensive care unit and a group of sex- and age-matched healthy control subject...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2018-10-01
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| Series: | Journal of International Medical Research |
| Online Access: | https://doi.org/10.1177/0300060518792783 |
| _version_ | 1818838028662079488 |
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| author | Ifigenia Kostoglou-Athanassiou Eleni Pantazi Sofoklis Kontogiannis Dimitrios Kousouris Iordanis Mavropoulos Panagiotis Athanassiou |
| author_facet | Ifigenia Kostoglou-Athanassiou Eleni Pantazi Sofoklis Kontogiannis Dimitrios Kousouris Iordanis Mavropoulos Panagiotis Athanassiou |
| author_sort | Ifigenia Kostoglou-Athanassiou |
| collection | DOAJ |
| description | Objective To investigate 25(OH)D 3 levels and their relationship to survival in a cohort of acutely ill patients on admission to an intensive care unit. Methods This study enrolled acutely ill patients at admission to an intensive care unit and a group of sex- and age-matched healthy control subjects. The 25(OH)D 3 levels were measured using an enzyme immunoassay. C-reactive protein and procalcitonin levels were also measured using immunoassays. Results A total of 50 acutely ill patients and 50 healthy control subjects were enrolled in the study. The mean ± SEM 25(OH)D 3 levels were significantly lower in the acutely ill patients compared with the control group (11.74 ± 0.88 ng/ml versus 24.66 ± 1.60 ng/ml, respectively). The 25(OH)D 3 levels were not related to survival. An inverse relationship was observed between 25(OH)D 3 levels and C-reactive protein levels. A weak inverse relationship was also observed between 25(OH)D 3 levels and procalcitonin levels. Conclusions The 25(OH)D 3 levels were decreased in acutely ill patients admitted to an intensive care unit compared with healthy control subjects. 25(OH)D 3 levels may be inversely related to C-reactive protein and procalcitonin levels. |
| first_indexed | 2024-12-19T03:31:53Z |
| format | Article |
| id | doaj.art-9a5bc7ffbf4346588aa5e92122c74e74 |
| institution | Directory Open Access Journal |
| issn | 0300-0605 1473-2300 |
| language | English |
| last_indexed | 2024-12-19T03:31:53Z |
| publishDate | 2018-10-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of International Medical Research |
| spelling | doaj.art-9a5bc7ffbf4346588aa5e92122c74e742022-12-21T20:37:29ZengSAGE PublishingJournal of International Medical Research0300-06051473-23002018-10-014610.1177/0300060518792783Vitamin D in acutely ill patientsIfigenia Kostoglou-AthanassiouEleni PantaziSofoklis KontogiannisDimitrios KousourisIordanis MavropoulosPanagiotis AthanassiouObjective To investigate 25(OH)D 3 levels and their relationship to survival in a cohort of acutely ill patients on admission to an intensive care unit. Methods This study enrolled acutely ill patients at admission to an intensive care unit and a group of sex- and age-matched healthy control subjects. The 25(OH)D 3 levels were measured using an enzyme immunoassay. C-reactive protein and procalcitonin levels were also measured using immunoassays. Results A total of 50 acutely ill patients and 50 healthy control subjects were enrolled in the study. The mean ± SEM 25(OH)D 3 levels were significantly lower in the acutely ill patients compared with the control group (11.74 ± 0.88 ng/ml versus 24.66 ± 1.60 ng/ml, respectively). The 25(OH)D 3 levels were not related to survival. An inverse relationship was observed between 25(OH)D 3 levels and C-reactive protein levels. A weak inverse relationship was also observed between 25(OH)D 3 levels and procalcitonin levels. Conclusions The 25(OH)D 3 levels were decreased in acutely ill patients admitted to an intensive care unit compared with healthy control subjects. 25(OH)D 3 levels may be inversely related to C-reactive protein and procalcitonin levels.https://doi.org/10.1177/0300060518792783 |
| spellingShingle | Ifigenia Kostoglou-Athanassiou Eleni Pantazi Sofoklis Kontogiannis Dimitrios Kousouris Iordanis Mavropoulos Panagiotis Athanassiou Vitamin D in acutely ill patients Journal of International Medical Research |
| title | Vitamin D in acutely ill patients |
| title_full | Vitamin D in acutely ill patients |
| title_fullStr | Vitamin D in acutely ill patients |
| title_full_unstemmed | Vitamin D in acutely ill patients |
| title_short | Vitamin D in acutely ill patients |
| title_sort | vitamin d in acutely ill patients |
| url | https://doi.org/10.1177/0300060518792783 |
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