A systematic and thematic analysis of the top 100 cited articles on mRNA vaccine indexed in Scopus database
The success of mRNA vaccines against SARS-CoV-2 implies that this technology can be applied to target any pathogen. However, the scientific production and research trends using the bibliometric method are still unknown. The top 100 most cited articles on mRNA vaccine research were obtained from the...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2022-11-01
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| Series: | Human Vaccines & Immunotherapeutics |
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| Online Access: | http://dx.doi.org/10.1080/21645515.2022.2135927 |
| _version_ | 1797673122167521280 |
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| author | Hassan H. Musa Taha H. Musa |
| author_facet | Hassan H. Musa Taha H. Musa |
| author_sort | Hassan H. Musa |
| collection | DOAJ |
| description | The success of mRNA vaccines against SARS-CoV-2 implies that this technology can be applied to target any pathogen. However, the scientific production and research trends using the bibliometric method are still unknown. The top 100 most cited articles on mRNA vaccine research were obtained from the Scopus database from 1995 to 2021. Bibliometrix, an R-Package, and VOSviewer 1.6.11 were used for data analysis. There is a rapid growth in scientific outputs with a gradual increase in 2021. The United States produced 45 (45%) of the articles, followed by Germany with 15 (15%) and Israel with 10 (10%). The New England Journal of Medicine published the most papers in this field 13 (13%), followed by Nature 6(6%). Barney S. Graham was the most productive author among the top 100 most cited mRNA vaccine articles. University of Pennsylvania Perelman School of Medicine, US, was the top ranking institution, having 37 (37%). The visualization map clearly and spontaneously displayed the current state and research hot spots of mRNA research from a specific perspective. The most frequent keywords were COVID-19, vaccine, mRNA vaccine, mRNA, SARS-CoV-2, and immunogenicity, among others. A systematic review of the articles provided evidence that out of 100 articles, approximately 25 (25%) were focused on vaccine production and evaluation, followed by 26 (26%) in mRNA vaccine safety and efficacy, 23 (23%) were into mRNA vaccination, 23 (23%) considered risk factors associated with mRNA vaccination, while 8 (8%) of the articles covered the issue of mRNA vaccine delivery. In addition, 42% of the articles focused on COVID-19, 17% on cancer, 8% on influenza virus, 4% on COVID-19 and kidney disease, 3% COVID-19 and myocarditis, and 3% on rabies virus, among others. The findings of this systematic and thematic analysis provided the knowledge basis for further research on mRNA vaccines globally. |
| first_indexed | 2024-03-11T21:40:49Z |
| format | Article |
| id | doaj.art-9a5e600ca7c9448e867c78273d0e927e |
| institution | Directory Open Access Journal |
| issn | 2164-5515 2164-554X |
| language | English |
| last_indexed | 2024-03-11T21:40:49Z |
| publishDate | 2022-11-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Human Vaccines & Immunotherapeutics |
| spelling | doaj.art-9a5e600ca7c9448e867c78273d0e927e2023-09-26T13:19:10ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2022-11-0118610.1080/21645515.2022.21359272135927A systematic and thematic analysis of the top 100 cited articles on mRNA vaccine indexed in Scopus databaseHassan H. Musa0Taha H. Musa1Chinese Academy of SciencesDarfur University CollegeThe success of mRNA vaccines against SARS-CoV-2 implies that this technology can be applied to target any pathogen. However, the scientific production and research trends using the bibliometric method are still unknown. The top 100 most cited articles on mRNA vaccine research were obtained from the Scopus database from 1995 to 2021. Bibliometrix, an R-Package, and VOSviewer 1.6.11 were used for data analysis. There is a rapid growth in scientific outputs with a gradual increase in 2021. The United States produced 45 (45%) of the articles, followed by Germany with 15 (15%) and Israel with 10 (10%). The New England Journal of Medicine published the most papers in this field 13 (13%), followed by Nature 6(6%). Barney S. Graham was the most productive author among the top 100 most cited mRNA vaccine articles. University of Pennsylvania Perelman School of Medicine, US, was the top ranking institution, having 37 (37%). The visualization map clearly and spontaneously displayed the current state and research hot spots of mRNA research from a specific perspective. The most frequent keywords were COVID-19, vaccine, mRNA vaccine, mRNA, SARS-CoV-2, and immunogenicity, among others. A systematic review of the articles provided evidence that out of 100 articles, approximately 25 (25%) were focused on vaccine production and evaluation, followed by 26 (26%) in mRNA vaccine safety and efficacy, 23 (23%) were into mRNA vaccination, 23 (23%) considered risk factors associated with mRNA vaccination, while 8 (8%) of the articles covered the issue of mRNA vaccine delivery. In addition, 42% of the articles focused on COVID-19, 17% on cancer, 8% on influenza virus, 4% on COVID-19 and kidney disease, 3% COVID-19 and myocarditis, and 3% on rabies virus, among others. The findings of this systematic and thematic analysis provided the knowledge basis for further research on mRNA vaccines globally.http://dx.doi.org/10.1080/21645515.2022.2135927mrna vaccinebibliometrixvosviewerscopus database |
| spellingShingle | Hassan H. Musa Taha H. Musa A systematic and thematic analysis of the top 100 cited articles on mRNA vaccine indexed in Scopus database Human Vaccines & Immunotherapeutics mrna vaccine bibliometrix vosviewer scopus database |
| title | A systematic and thematic analysis of the top 100 cited articles on mRNA vaccine indexed in Scopus database |
| title_full | A systematic and thematic analysis of the top 100 cited articles on mRNA vaccine indexed in Scopus database |
| title_fullStr | A systematic and thematic analysis of the top 100 cited articles on mRNA vaccine indexed in Scopus database |
| title_full_unstemmed | A systematic and thematic analysis of the top 100 cited articles on mRNA vaccine indexed in Scopus database |
| title_short | A systematic and thematic analysis of the top 100 cited articles on mRNA vaccine indexed in Scopus database |
| title_sort | systematic and thematic analysis of the top 100 cited articles on mrna vaccine indexed in scopus database |
| topic | mrna vaccine bibliometrix vosviewer scopus database |
| url | http://dx.doi.org/10.1080/21645515.2022.2135927 |
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