Effect of implantation Ti-6Al-4V ELI in femoral bone defect regeneration of Sprague Dawley rat

Ti-6Al-4V ELI is one of the most commonly used dental implant restore function. The solution treatment temperature variation can significantly increase the strength, but it is not yet known the effect of these temperature variations on the alloy's biocompatibility properties. Twelve female Spra...

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Main Authors: I Nyoman Jujur, Damisih, Kartika Devy, Shovy Suha, Boy Muchlis Bachtiar, Endang Winiati Bachtiar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Journal of Advanced Pharmaceutical Technology & Research
Subjects:
Online Access:http://www.japtr.org/article.asp?issn=2231-4040;year=2020;volume=11;issue=4;spage=202;epage=206;aulast=Jujur
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author I Nyoman Jujur
Damisih
Kartika Devy
Shovy Suha
Boy Muchlis Bachtiar
Endang Winiati Bachtiar
author_facet I Nyoman Jujur
Damisih
Kartika Devy
Shovy Suha
Boy Muchlis Bachtiar
Endang Winiati Bachtiar
author_sort I Nyoman Jujur
collection DOAJ
description Ti-6Al-4V ELI is one of the most commonly used dental implant restore function. The solution treatment temperature variation can significantly increase the strength, but it is not yet known the effect of these temperature variations on the alloy's biocompatibility properties. Twelve female Sprague Dawley rats were divided into six groups as follows: the treated group, the control group, and the defect group without implant material. In the treated group, the femur bone defect was implanted with as-cast Ti-6Al-4V ELI, 850°C, 950°C, and 1050°C heat-treated Ti-6Al-4V ELI implant material. The rats were euthanized after 30 days postimplantation and evaluated histologically. The results show that the histological scoring of the specimen for femur defect without implant material is 2 (fibrous union and fibrocartilaginous), score with implant as-cast is 2.5, the sample with 850°C heat treatment material is 2.5, 950°C is 2.5, and the temperature at 1050°C is 2.5. The score of 2.5 is between score 2 and score 3: hemorrhage, fibrous union, fibrocartilaginous microhemorrhage, and mineralized cartilage union. In conclusion, there is no effect of different heat treatment temperatures for Ti-6Al-4V ELI implant material in rat bone regeneration's maturation level.
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spelling doaj.art-9a5f9ef7ab0045368f056de5111036fd2022-12-21T23:39:17ZengWolters Kluwer Medknow PublicationsJournal of Advanced Pharmaceutical Technology & Research2231-40400976-20942020-01-0111420220610.4103/japtr.JAPTR_74_20Effect of implantation Ti-6Al-4V ELI in femoral bone defect regeneration of Sprague Dawley ratI Nyoman JujurDamisihKartika DevyShovy SuhaBoy Muchlis BachtiarEndang Winiati BachtiarTi-6Al-4V ELI is one of the most commonly used dental implant restore function. The solution treatment temperature variation can significantly increase the strength, but it is not yet known the effect of these temperature variations on the alloy's biocompatibility properties. Twelve female Sprague Dawley rats were divided into six groups as follows: the treated group, the control group, and the defect group without implant material. In the treated group, the femur bone defect was implanted with as-cast Ti-6Al-4V ELI, 850°C, 950°C, and 1050°C heat-treated Ti-6Al-4V ELI implant material. The rats were euthanized after 30 days postimplantation and evaluated histologically. The results show that the histological scoring of the specimen for femur defect without implant material is 2 (fibrous union and fibrocartilaginous), score with implant as-cast is 2.5, the sample with 850°C heat treatment material is 2.5, 950°C is 2.5, and the temperature at 1050°C is 2.5. The score of 2.5 is between score 2 and score 3: hemorrhage, fibrous union, fibrocartilaginous microhemorrhage, and mineralized cartilage union. In conclusion, there is no effect of different heat treatment temperatures for Ti-6Al-4V ELI implant material in rat bone regeneration's maturation level.http://www.japtr.org/article.asp?issn=2231-4040;year=2020;volume=11;issue=4;spage=202;epage=206;aulast=Jujurbone regenerationheat treatmentti-6al-4v elititanium implant
spellingShingle I Nyoman Jujur
Damisih
Kartika Devy
Shovy Suha
Boy Muchlis Bachtiar
Endang Winiati Bachtiar
Effect of implantation Ti-6Al-4V ELI in femoral bone defect regeneration of Sprague Dawley rat
Journal of Advanced Pharmaceutical Technology & Research
bone regeneration
heat treatment
ti-6al-4v eli
titanium implant
title Effect of implantation Ti-6Al-4V ELI in femoral bone defect regeneration of Sprague Dawley rat
title_full Effect of implantation Ti-6Al-4V ELI in femoral bone defect regeneration of Sprague Dawley rat
title_fullStr Effect of implantation Ti-6Al-4V ELI in femoral bone defect regeneration of Sprague Dawley rat
title_full_unstemmed Effect of implantation Ti-6Al-4V ELI in femoral bone defect regeneration of Sprague Dawley rat
title_short Effect of implantation Ti-6Al-4V ELI in femoral bone defect regeneration of Sprague Dawley rat
title_sort effect of implantation ti 6al 4v eli in femoral bone defect regeneration of sprague dawley rat
topic bone regeneration
heat treatment
ti-6al-4v eli
titanium implant
url http://www.japtr.org/article.asp?issn=2231-4040;year=2020;volume=11;issue=4;spage=202;epage=206;aulast=Jujur
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