Conducting clinical trials in sub-Saharan Africa: challenges and lessons learned from the Malawi Cryptosporidium study

Conducting clinical trials in sub-Saharan Africa: challenges and lessons learned from the Malawi Cryptosporidium study

Abstract Background An effective drug to treat cryptosporidial diarrhea in HIV-infected individuals is a global health priority. Promising drugs need to be evaluated in endemic areas which may be challenged by both lack of resources and experience to conduct International Committee of Harmonisation-...

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Bibliographic Details
Main Authors: Neema Toto, Elaine Douglas, Markus Gmeiner, Lynn K. Barrett, Robert Lindblad, Lumbani Makhaza, Wilfred Nedi, Jacob Phulusa, Gerald V. Quinnan, Leigh A. Sawyer, Herbert Thole, Wesley C. Van Voorhis, Pui-Ying Iroh Tam
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Trials
Subjects:
Clinical trial
Developing country
Sub-Saharan Africa
Low-resource setting
Cryptosporidiosis
Diarrhea
Online Access:http://link.springer.com/article/10.1186/s13063-020-04620-8

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