The 1450-nm Diode Laser Reduces Redness and Porphyrin Density: An Image-Based, Patient-Oriented Appraisal
Background: Acne vulgaris remains the leading dermatological condition. The efficacy of laser treatment has been supported by many clinical studies, but studies investigating its multidimensional action are lacking. Aim: To comprehensively investigate the efficacy of 1450-nm diode laser treatment in...
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| Format: | Article |
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MDPI AG
2023-07-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/12/13/4500 |
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| author | Gong-Yau Chu Chieh-Chen Huang Nai-Hua Shih Chung-Hua Hsu Ching-Ying Wu |
| author_facet | Gong-Yau Chu Chieh-Chen Huang Nai-Hua Shih Chung-Hua Hsu Ching-Ying Wu |
| author_sort | Gong-Yau Chu |
| collection | DOAJ |
| description | Background: Acne vulgaris remains the leading dermatological condition. The efficacy of laser treatment has been supported by many clinical studies, but studies investigating its multidimensional action are lacking. Aim: To comprehensively investigate the efficacy of 1450-nm diode laser treatment in patients with inflammatory acne and provide objective and subjective data for doctors in clinical practice. Methods: This retrospective study included patients with inflammatory acne lesions who underwent three courses of 1450-nm diode laser treatment between October 2019 and August 2020. Facial surface analysis was performed via objective computer assessments using the Canfield VISIA imaging system. Post-treatment subjective assessments were retrieved and analyzed using the clinical global impression–improvement index (CGI-I) and patient global impression of improvement scales (PGI-I). Results: The final analysis included 20 patients. The changes in the porphyrin VISIA system scores demonstrated significant improvement, with median scores being 35.83, 48.83, and 54.83, respectively. The changes in the red area VISIA scores also showed improvement, with the median scores being 48, 50.33, and 58.83, respectively. The average CGI-I scale scores were 2.2 ± 1.01, 1.70 ± 0.80, and 1.50 ± 0.76, respectively (<i>p</i> = 0.001), and the average PGI-I scale scores were 3.10 ± 0.85, 3.10 ± 0.97, and 3.05 ± 0.95, respectively (<i>p</i> = 0.727), with no significant changes observed in sebum production. Conclusions: The present study is the first to provide objective and subjective evidence proving that the 1450-nm diode laser can reduce inflammatory acne lesions. |
| first_indexed | 2024-03-11T01:37:19Z |
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| language | English |
| last_indexed | 2024-03-11T01:37:19Z |
| publishDate | 2023-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-9a62f7f6e1ee4cc5af71b096235d61fb2023-11-18T16:54:46ZengMDPI AGJournal of Clinical Medicine2077-03832023-07-011213450010.3390/jcm12134500The 1450-nm Diode Laser Reduces Redness and Porphyrin Density: An Image-Based, Patient-Oriented AppraisalGong-Yau Chu0Chieh-Chen Huang1Nai-Hua Shih2Chung-Hua Hsu3Ching-Ying Wu4Institute of Traditional Medicine, School of Medicine, National Yang-Ming Chiao Tung University, Taipei 30010, TaiwanDepartment of Dermatology, Shin-Kong Wu Ho-Su Memorial Hospital, Taipei 11101, TaiwanDepartment of Laboratory Medicine, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung 80145, TaiwanInstitute of Traditional Medicine, School of Medicine, National Yang-Ming Chiao Tung University, Taipei 30010, TaiwanDepartment of Dermatology, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 80756, TaiwanBackground: Acne vulgaris remains the leading dermatological condition. The efficacy of laser treatment has been supported by many clinical studies, but studies investigating its multidimensional action are lacking. Aim: To comprehensively investigate the efficacy of 1450-nm diode laser treatment in patients with inflammatory acne and provide objective and subjective data for doctors in clinical practice. Methods: This retrospective study included patients with inflammatory acne lesions who underwent three courses of 1450-nm diode laser treatment between October 2019 and August 2020. Facial surface analysis was performed via objective computer assessments using the Canfield VISIA imaging system. Post-treatment subjective assessments were retrieved and analyzed using the clinical global impression–improvement index (CGI-I) and patient global impression of improvement scales (PGI-I). Results: The final analysis included 20 patients. The changes in the porphyrin VISIA system scores demonstrated significant improvement, with median scores being 35.83, 48.83, and 54.83, respectively. The changes in the red area VISIA scores also showed improvement, with the median scores being 48, 50.33, and 58.83, respectively. The average CGI-I scale scores were 2.2 ± 1.01, 1.70 ± 0.80, and 1.50 ± 0.76, respectively (<i>p</i> = 0.001), and the average PGI-I scale scores were 3.10 ± 0.85, 3.10 ± 0.97, and 3.05 ± 0.95, respectively (<i>p</i> = 0.727), with no significant changes observed in sebum production. Conclusions: The present study is the first to provide objective and subjective evidence proving that the 1450-nm diode laser can reduce inflammatory acne lesions.https://www.mdpi.com/2077-0383/12/13/4500acne vulgarisinflammatory acne1450-nm diode laser |
| spellingShingle | Gong-Yau Chu Chieh-Chen Huang Nai-Hua Shih Chung-Hua Hsu Ching-Ying Wu The 1450-nm Diode Laser Reduces Redness and Porphyrin Density: An Image-Based, Patient-Oriented Appraisal Journal of Clinical Medicine acne vulgaris inflammatory acne 1450-nm diode laser |
| title | The 1450-nm Diode Laser Reduces Redness and Porphyrin Density: An Image-Based, Patient-Oriented Appraisal |
| title_full | The 1450-nm Diode Laser Reduces Redness and Porphyrin Density: An Image-Based, Patient-Oriented Appraisal |
| title_fullStr | The 1450-nm Diode Laser Reduces Redness and Porphyrin Density: An Image-Based, Patient-Oriented Appraisal |
| title_full_unstemmed | The 1450-nm Diode Laser Reduces Redness and Porphyrin Density: An Image-Based, Patient-Oriented Appraisal |
| title_short | The 1450-nm Diode Laser Reduces Redness and Porphyrin Density: An Image-Based, Patient-Oriented Appraisal |
| title_sort | 1450 nm diode laser reduces redness and porphyrin density an image based patient oriented appraisal |
| topic | acne vulgaris inflammatory acne 1450-nm diode laser |
| url | https://www.mdpi.com/2077-0383/12/13/4500 |
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